| Identification | More | [Name]
Potassium trifluoroacetate | [CAS]
2923-16-2 | [Synonyms]
POTASSIUM TRIFLUOROACETATE
TRIFLUOROACETIC ACID POTASSIUM SALT
TRIFLUOROACETIC ACID POTASSIUM
Potassium trifluoroacetate 98%
Potassiumtrifluoroacetate98% | [EINECS(EC#)]
220-877-5 | [Molecular Formula]
C2F3KO2 | [MDL Number]
MFCD00013215 | [Molecular Weight]
152.11 | [MOL File]
2923-16-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystalline powder | [Melting point ]
140-142 °C (lit.) | [density ]
1.49 g/mL(lit.)
| [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
H2O: 0.1 g/mL, clear, colorless
| [form ]
solid | [color ]
White to Pale Yellow | [Specific Gravity]
1.49 | [Water Solubility ]
Soluble in water. | [Hydrolytic Sensitivity]
0: forms stable aqueous solutions | [Sensitive ]
Hygroscopic | [BRN ]
3717603 | [Stability:]
Very Hygroscopic | [InChIKey]
CUNPJFGIODEJLQ-UHFFFAOYSA-M | [LogP]
-3.12 at 20℃ | [CAS DataBase Reference]
2923-16-2(CAS DataBase Reference) | [EPA Substance Registry System]
Acetic acid, 2,2,2-trifluoro-, potassium salt (1:1) (2923-16-2) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
3288 | [WGK Germany ]
3
| [F ]
3-10 | [Hazard Note ]
Irritant/Hygroscopic | [TSCA ]
No | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT, MOISTURE SENSITIVE, HYGROSCOPIC | [PackingGroup ]
II | [HS Code ]
29159000 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
It is a reagent for preparation of aryl trifluoromethyl sulfides, by heating with the diaryl disulfide. | [Flammability and Explosibility]
Nonflammable | [Synthesis]
Example 14: Synthesis of potassium trifluoroacetate (CF3-COOK(5)); In a 500 mL glass flask, 20 mL of water, 73 mL of acetonitrile (MeCN), 1.33 g of potassium bromide (KBr), 0.46 g of TEMPO, and 10 g of 2,2,2-trifluoroethanol were sequentially added. The flask was equipped with a dropping funnel and a stirrer. An aqueous solution of sodium hypochlorite (NaOCl) (15 wt%, 175 mL) with pH adjusted to 8-9 was added in three batches through the dropping funnel under stirring at room temperature and the addition process took two days. Upon completion of the reaction, concentrated sulfuric acid and water were added to the reaction mixture to adjust the pH to 1-2. The reaction mixture was extracted three times with ether. The ether phases were combined and dried with magnesium sulfate, followed by distillation at atmospheric pressure to remove the ether. To the distillate was added 60 mL of methanol and 7 g of potassium methanolate and stirred for 1 h at room temperature. The solvent was evaporated after filtration to give potassium trifluoroacetate (13.13 g, 86% yield) as a colorless solid.19F NMR (D2O): -76.82 (s, 3F). | [Purification Methods]
To purify it, dissolve the salt in trifluoroacetic acid with ca 2% of trifluoroacetic anhydride, filter it and evaporate it carefully to dryness (avoid over heating), and finally dry it in a vacuum at 100o. It can be recrystallised from trifluoroacetic acid (solubility in the acid is ca 50.1%). [Simons & Lorentzen J Am Chem Soc 74 4746 1952, Hara & Cady J Am Chem Soc 76 4285 1954, Watt & Muga J Inorg Nucl Chem 9 166 1959, Beilstein 2 IV 458.] | [References]
[1] Patent: WO2011/50131, 2011, A2. Location in patent: Page/Page column 40
[2] Journal of Fluorine Chemistry, 2012, vol. 141, p. 35 - 40 |
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