| Identification | More | [Name]
2-(4-FLUOROBENZYLAMINO)ETHANOL | [CAS]
22116-33-2 | [Synonyms]
CHEMBRDG-BB 4004526
2-(4-FLUOROBENZYLAMINO)ETHANOL
2-(4-Fluorobenzyl)-Ethanolamino
2-(4-FLUOROBENZYLAMINO)ETHANOL,98%
2-[(4-fluorophenyl)methylamino]ethanol
Ethanol-2-(4-(fluorophenyl)methyl)amine
Ethanol, 2-[[(4-fluorophenyl)Methyl]aMino]-
2-[(4-fluorobenzyl)amino]ethanol(SALTDATA: FREE) | [Molecular Formula]
C9H12FNO | [MDL Number]
MFCD04560903 | [Molecular Weight]
169.2 | [MOL File]
22116-33-2.mol |
| Chemical Properties | Back Directory | [Boiling point ]
95-98 °C(Press: 3 Torr) | [density ]
1.1358 g/cm3 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Low-Melting Solid | [pka]
14.75±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C9H12FNO/c10-9-3-1-8(2-4-9)7-11-5-6-12/h1-4,11-12H,5-7H2 | [InChIKey]
KWEPMOQQKUYWIN-UHFFFAOYSA-N | [SMILES]
C(O)CNCC1=CC=C(F)C=C1 | [CAS DataBase Reference]
22116-33-2(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
2-[(4-Fluorobenzyl)amino]ethanol is used in preparation of (Fluorobenzyl)aminomethylmorpholine salt and its application in preparation of mosapride citrate. |
| Hazard Information | Back Directory | [Application]
2-(4-FLUOROBENZYLAMINO)ETHANOL can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
P-fluorobenzaldehyde (24.8 g, 0.2 mol) and 2-aminoethanol (15.3 g, 0.25 mol) were added to a reaction flask containing methanol (250 ml), heated to reflux, and kept at 65 ?? C for 4 h.The temperature was lowered, sodium borohydride (9.2 g 0.24 mol) was added, and the reaction was stirred, the reaction was completed, filtered, and concentrated.The fraction was collected to give 2-(4-fluorobenzylamino)ethanol as a colorless oily liquid (yield: 90.2%, purity 98.7%). |
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