| Identification | Back Directory | [Name]
N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5 | [CAS]
2107273-12-9 | [Synonyms]
N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5 | [Molecular Formula]
C40H57ClN2O7 | [MDL Number]
MFCD29079424 | [MOL File]
2107273-12-9.mol | [Molecular Weight]
713.35 |
| Hazard Information | Back Directory | [Description]
N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5 is a cyanine labeled PEG linker with excitation/emmission maximum 649/667 nm containing hydroxyl group, which enables further derivatized or replaced with other reactive functional groups. Hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. | [Uses]
N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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