| Identification | More | [Name]
Bis(4-bromophenyl) ether | [CAS]
2050-47-7 | [Synonyms]
4,4'-DIBROMODIPHENYL ETHER
4,4'-DIBROMODIPHENYL OXIDE
4,4'-DIBROMOPHENYL ETHER
4-BROMOPHENYL ETHER
BIS(4-BROMOPHENYL) ETHER
BIS(P-BROMOPHENYL)ETHER
DI-(P-BROMOPHENYL)ETHER
1,1’-oxybis(4-bromo-Benzene
1,1’-oxybis[4-bromo-benzen
1-Bromo-4-(4-bromophenoxy)benzene
Benzene, 1,1'-oxybis[4-bromo-
Bis-(4-bromphenyl)-ether
Bis(bromophenyl) ether
di(4-Bromophenyl)ether
Diphenyl ether, 4,4'-dibromo
Ether, bis(4-bromophenyl)
Ether, bis(p-bromophenyl)
ether,bis(4-bromophenyl)
p,p’-Dibromodiphenylether
p,p'-Dibromodiphenyl ether | [EINECS(EC#)]
218-090-7 | [Molecular Formula]
C12H8Br2O | [MDL Number]
MFCD00000095 | [Molecular Weight]
328 | [MOL File]
2050-47-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Tan or light crystalline | [Melting point ]
61-63 °C(lit.)
| [Boiling point ]
338-340 °C(lit.)
| [density ]
1.6728 (rough estimate) | [refractive index ]
1.6260 (estimate) | [Fp ]
338-340°C | [storage temp. ]
2-8°C | [solubility ]
Methanol (Slightly) | [form ]
Crystalline | [color ]
White | [Water Solubility ]
Soluble in water. | [InChI]
InChI=1S/C12H8Br2O/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H | [InChIKey]
YAWIAFUBXXPJMQ-UHFFFAOYSA-N | [SMILES]
O(C1=CC=C(Br)C=C1)C1=CC=C(Br)C=C1 | [CAS DataBase Reference]
2050-47-7(CAS DataBase Reference) | [NIST Chemistry Reference]
4-Bromophenyl ether(2050-47-7) | [EPA Substance Registry System]
2050-47-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn,N | [Risk Statements ]
R33:Danger of cumulative effects.
R67:Vapors may cause drowsiness and dizziness.
R65:Harmful: May cause lung damage if swallowed.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R38:Irritating to the skin.
R11:Highly Flammable. | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S62:If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S60:This material and/or its container must be disposed of as hazardous waste . | [RIDADR ]
UN 1262 3/PG 2 | [WGK Germany ]
3
| [RTECS ]
KN0175000
| [TSCA ]
Yes | [HS Code ]
29093090 | [Toxicity]
LD50 ipr-mus: 125 mg/kg NTIS** AD277-689 |
| Hazard Information | Back Directory | [Chemical Properties]
Tan or light crystalline | [Uses]
PBDE 15 is a polybrominated di-?Ph ether (PBDE), which is a flame retardant often incorporated into many polymers. PBDEs are an environmental pollutant that exhibit potential health risks to humans and wildlife. | [Safety Profile]
Poison by intraperitoneal route. When heated todecomposition it emits toxic fumes of Br-. | [Synthesis]
The general procedure for the synthesis of 4,4'-dibromodiphenyl ether from diphenyl ether was as follows: in a four-necked round-bottomed flask fitted with a stirrer, condenser, dropping funnel and thermometer, diphenyl ether (170 g, 1.0 mol), 1,2-dichloroethane (EDC) (300 ml), water (200 ml) and NaBrO3 (55 g, 0.36 mol) were added. Bromine (176 g, 1.1 mol) was slowly added dropwise to the stirred mixture for 1 h at 25 °C. No significant HBr gas was released during the reaction. The reaction progress was monitored by gas chromatography (GC). After two hours of reaction, the diphenyl ether was completely converted to 4,4'-dibromodiphenyl ether. The reaction was stopped and the phases were separated to give the crude product 4,4'-dibromodiphenyl ether (324.8 g) in 99% yield and 99.5% selectivity. | [References]
[1] Patent: EP429975, 1991, A1
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 20, p. 5938 - 5942
[3] Angew. Chem., 2018, vol. 130, p. 6044 - 6049,6
[4] Monatshefte fuer Chemie, 1992, vol. 123, # 12, p. 1153 - 1162
[5] Patent: EP429975, 1991, A1 |
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