| Identification | More | [Name]
LITHIUM DODECYL SULFATE | [CAS]
2044-56-6 | [Synonyms]
DODECYL LITHIUM SULFATE
DODECYL SULFATE LITHIUM SALT
DODECYL SULPHATE, LITHIUM SALT
LAURYL SULFATE LITHIUM SALT
LAURYL SULPHATE, LITHIUM SALT
LDS
LITHIUM DODECYL SULFATE
LITHIUM DODECYL SULPHATE
LITHIUM LAURYL SULFATE
LITHIUM LAURYL SULPHATE
Laurylalcoholsulfate,lithiumsalt
Sulfuricacid,monododecylester,lithiumsalt
LAURYL SULFATE LITHIUM SIGMAULTRA
LAURYL SULFATE LITHIUM ELECTROPHORESIS*R EAGENT
LAURYL SULFATE LITHIUM, MOLECULAR*BIOLOG Y REAGENT
Lithium dodecyl sulfate, 99+%
LITHIUMDODECYLSULFATE,ULTRAPURE
LITHIUM DODECYL SULFATE (LAURYL SULFATE LITHIUM SALT)
Lithium dodecyl sulphate >98%
LITHIUM LAURYL SULPHATE extrapure | [EINECS(EC#)]
218-058-2 | [Molecular Formula]
C12H25LiO4S | [MDL Number]
MFCD00007467 | [Molecular Weight]
272.33 | [MOL File]
2044-56-6.mol |
| Chemical Properties | Back Directory | [Appearance]
solid | [Boiling point ]
199℃[at 101 325 Pa] | [density ]
1.168[at 20℃] | [vapor pressure ]
6.5Pa at 20℃ | [storage temp. ]
Store at RT. | [solubility ]
H2O: 0.1 M at 20 °C, clear, colorless
| [form ]
Shiny Crystalline Flakes or Powder | [color ]
White | [PH]
pH(0.25mol/l, 25℃) : 5.0～10.5 | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
Soluble in water. | [BRN ]
5186718 | [InChI]
InChI=1S/C12H26O4S.Li/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1 | [InChIKey]
YFVGRULMIQXYNE-UHFFFAOYSA-M | [SMILES]
C(COS([O-])(=O)=O)CCCCCCCCCC.[Li+] | [CAS DataBase Reference]
2044-56-6(CAS DataBase Reference) | [EPA Substance Registry System]
Sulfuric acid, monododecyl ester, lithium salt (2044-56-6) | [Absorption]
≤0.05 at 260nm (3% solution)
≤0.05 at 280nm (3% solution) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,C,F | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R15:Contact with water liberates extremely flammable gases.
R14:Reacts violently with water.
R11:Highly Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add-Never use water) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking .
S7/8:Keep container tightly closed and dry . | [RIDADR ]
UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all | [WGK Germany ]
3
| [F ]
3 | [TSCA ]
Yes | [HazardClass ]
4.1 | [HS Code ]
29209090 |
| Hazard Information | Back Directory | [Description]
Lithium dodecyl sulfate (LDS) is an anionic detergent and surfactant that is frequently used in electrophoresis and chromatography. LDS may be substituted for sodium dodecyl sulfate (SDS) in electrophoresis under cold conditions. The use of LDS in micellar electrokinetic chromatography has been extensively studied. A report has been published on the partition equilibria of LDS between water and bilayer membranes. LDS has been utilized in protein electrophoresis and proteomics studies. The three-dimensional structure of the amyloid β-protein fragment 25-35 has been investigated in LDS micelles by two-dimensional 1HNMR. LDS has been used to induce changes in protein conformation. | [Chemical Properties]
solid | [Uses]
Lithium dodecyl sulfate has been used as a component of lysis buffer. | [Flammability and Explosibility]
Flammable | [Purification Methods]
Recrystallise this detergent twice from absolute EtOH and dry it under vacuum. Critical Micellar Concentration (CMC) in H2O is 8.77 x 10-3M. [Mukerjee et al. J Phys Chem 71 4166 1967, Mysels & Dulin J Colloid Sci 10 461 1955, Beilstein 1 IV 1847.] | [Precautions]
In general, autoclaved lauryl sulfate solutions undergo hydrolysis to yield lauryl alcohol, which precipitates from solution, and sulfuric acid, which decreases the solution pH. It is not advised to autoclave lauryl sulfate solutions. | [References]
[1] ELISABET FUGUET. Solute?Solvent Interactions in Micellar Electrokinetic Chromatography. 6. Optimization of the Selectivity of Lithium Dodecyl Sulfate?Lithium Perfluorooctanesulfonate Mixed Micellar Buffers[J]. Analytical Chemistry, 2002, 74 17: 4447-4455. DOI:10.1021/ac0201530.
[2] M D TRONE. Characterization of chemical selectivity in micellar electrokinetic chromatography. VI. Effects of surfactant counter-ion.[J]. Journal of Chromatography A, 2000, 888 1-2: 229-240. DOI:10.1016/s0021-9673(00)00515-x.
[3] GARY H. PERDEW Daniel P S Henry W Schaup. The use of a zwitterionic detergent in two-dimensional gel electrophoresis of trout liver microsomes[J]. Analytical biochemistry, 1983, 135 2: Pages 453-455. DOI:10.1016/0003-2697(83)90711-X.
[4] SHINJI KONDOU. Concentrated Lithium Dodecyl Sulfate Aqueous Electrolytes: Utilizing Self-Assembly and Interfacial Adsorption for Aqueous Li-ion Batteries[J]. ChemElectroChem, 2022, 9 20. DOI:10.1002/celc.202200870. |
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