| Identification | More | [Name]
4-(2-AMINO-ETHYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER | [CAS]
192130-34-0 | [Synonyms]
1-BOC-4-(2-AMINOETHYL)PIPERAZINE
4-(2-AMINO-ETHYL)-1-BOC-PIPERAZINE
4-(2-AMINO-ETHYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
4-(2-AMINOETHYL)PIPERAZINE, N1-BOC PROTECTED
4-N-(2-AMINOETHYL)-1-N-BOC-PIPERAZINE
BUTTPARK 90\06-05
CHEMBRDG-BB 4004160
TERT-BUTYL 4-(2-AMINOETHYL)PIPERAZINE-1-CARBOXYLATE
TERT-BUTYL 4-(2-AMINOETHYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE
4-(2-Aminoethyl)piperazine-1-carboxylicacidtert-butylester95%
4-(2-Aminoethyl)piperazine, N1-BOC protected 95% | [Molecular Formula]
C11H23N3O2 | [MDL Number]
MFCD02683049 | [Molecular Weight]
229.32 | [MOL File]
192130-34-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
36-41°C | [Boiling point ]
319.4±32.0 °C(Predicted) | [density ]
1.056±0.06 g/cm3(Predicted) | [Fp ]
>198℃ | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
low melting solid | [pka]
10.11±0.10(Predicted) | [color ]
Light yellow to yellow | [InChI]
InChI=1S/C11H23N3O2/c1-11(2,3)16-10(15)14-8-6-13(5-4-12)7-9-14/h4-9,12H2,1-3H3 | [InChIKey]
QSYTWBKZNNEKPN-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCN(CCN)CC1 | [CAS DataBase Reference]
192130-34-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2933599590 |
| Hazard Information | Back Directory | [Uses]
tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate is a useful research chemical for the synthesis of biologically active compounds. | [Synthesis]
GENERAL METHOD: N-substituted phthalimide (2.00 mmol) was mixed with 80% aqueous hydrazine hydrate (2 mL) in ethanol (20 mL) and the reaction was stirred at 70°C for 20 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered to remove the precipitate. The filtrate was concentrated under reduced pressure to remove the solvent to give the crude product, which can be used directly in subsequent reactions without further purification. | [References]
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 7, p. 2251 - 2259
[2] ChemMedChem, 2014, vol. 9, # 4, p. 752 - 761 |
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