| Identification | More | [Name]
2-[2-(Dimethylamino)ethoxy]ethanol | [CAS]
1704-62-7 | [Synonyms]
2-(2-DIMETHYLAMINOETHOXY)ETHANOL
ETHYLENE GLYCOL MONO[2-(DIMETHYLAMINO)ETHYL] ETHER
LABOTEST-BB LT00000073
LUPRAGEN(R) N 107
2-(2-dimethylaminoethoxy)-ethano
2-[2-(dimethylamino)ethoxy]-ethano
Dimethylaminoethoxyethanol
N,N-Dimethyldiglycolamine
Texacat ZR-70
Ethanol, 2-2-(dimethylamino)ethoxy-
N,N-Dimethyl-2-(2-aminoethoxy)ethanol
2-[2-(Dimethylamino)ethoxy]Ethanol (DMEE)
Dimethyl-2-(2-hydroxyethoxy)ethylamine | [EINECS(EC#)]
216-940-1 | [Molecular Formula]
C6H15NO2 | [MDL Number]
MFCD00059602 | [Molecular Weight]
133.19 | [MOL File]
1704-62-7.mol |
| Chemical Properties | Back Directory | [Appearance]
liquid | [Boiling point ]
95 °C15 mm Hg(lit.) | [density ]
0.954 g/mL at 25 °C(lit.)
| [vapor pressure ]
11Pa at 20℃ | [refractive index ]
n20/D 1.442(lit.)
| [Fp ]
199 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
clear liquid | [pka]
14.37±0.10(Predicted) | [color ]
Colorless to Light yellow to Light orange | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, acids, isocyanates. | [Water Solubility ]
1000g/L at 20℃ | [LogP]
-0.778 at 20℃ | [CAS DataBase Reference]
1704-62-7(CAS DataBase Reference) | [NIST Chemistry Reference]
ethanol, 2-[2-(dimethylamino)ethoxy]-(1704-62-7) | [EPA Substance Registry System]
1704-62-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R21:Harmful in contact with skin.
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
NA 1993 / PGIII | [WGK Germany ]
1
| [RTECS ]
KK6825000
| [HS Code ]
29225090 | [Toxicity]
rabbit,LD50,skin,1410uL/kg (1.41mL/kg),Toxicology and Applied Pharmacology. Vol. 28, Pg. 313, 1974. |
| Hazard Information | Back Directory | [Chemical Properties]
liquid | [Uses]
Used for the preparation of low-density packaging foams. | [Flammability and Explosibility]
Notclassified | [Synthesis]
1. Synthesis step: 63.1 g of diethylene glycolamine (0.6 mol) and 34.5 g of paraformaldehyde (1.2 mol) were added to a 250 mL three-necked flask and stirred for 30 minutes. Subsequently, 63 g of formic acid (1.2 mol, 88%) was added slowly and dropwise. The reaction mixture was heated to 100-110°C and kept at this temperature for 1 hour. Upon completion of the reaction, 30 g of the fraction was distilled under reduced pressure (vacuum -0.094 MPa, kettle temperature 80°C). At this time, the content of the product 2-[2-(dimethylamino)ethoxy]ethanol was 90.0% and the content of impurity (S-2) was 9.8%.
2. Purification step: the above reaction solution was transferred to a 500 mL distillation flask and distilled under reduced pressure (-0.094 MPa). Firstly, the fraction at 62°C was collected, which was mainly n-butanol ester exchange product and butyl formate. Subsequently, the fraction at 121 °C, the target product 2-[2-(dimethylamino)ethoxy]ethanol, was collected, and a total of 128.3 g was obtained in 96.5% yield and 99.9% product purity. | [References]
[1] Patent: CN106748831, 2017, A. Location in patent: Paragraph 0043-0058; 0064 |
|
|