| Identification | More | [Name]
Mafenide hydrochloride | [CAS]
138-37-4 | [Synonyms]
4-AMINOMETHYLBENZENESULFONAMIDE HYDROCHLORIDE
4-AMINOMETHYLBENZENESULFONAMINDE HYDROCHLORIDE
4-HOMOSULFANILAMIDE HYDROCHLORIDE
A-AMINO-P-TOLUENESULFONAMIDE HYDROCHLORIDE
ALPHA-AMINO-P-TOLUENESULFONAMIDE HYDROCHLORIDE
HOMOSULFAMINE HYDROCHLORIDE
LABOTEST-BB LT00454465
LABOTEST-BB LTBB000725
MAFENIDE
MAFENIDE HYDROCHLORIDE
MARFANIL
MARFANIL HYDROCHLORIDE
P-AMINOMETHYLBENZENE SULFONAMIDE HCL
P-AMINOMETHYLBENZENESULFONAMIDE HYDROCHLORIDE
alpha-amino-p-toluenesulfonamidmonohydrochloride
homosulfanilamidehydrochloride
masudin
morfanil
p-aminomethylphenylsulfonamidehydrochloride
sulfamylonhydrochloride | [EINECS(EC#)]
205-325-3 | [Molecular Formula]
C7H11ClN2O2S | [MDL Number]
MFCD00013005 | [Molecular Weight]
222.69 | [MOL File]
138-37-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
261-263 °C(lit.) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
White | [Merck ]
13,5671 | [InChI]
InChI=1S/C7H10N2O2S.ClH/c8-5-6-1-3-7(4-2-6)12(9,10)11;/h1-4H,5,8H2,(H2,9,10,11);1H | [InChIKey]
SIACJRVYIPXFKS-UHFFFAOYSA-N | [SMILES]
C1(S(=O)(=O)N)=CC=C(CN)C=C1.Cl | [CAS DataBase Reference]
138-37-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R42/43:May cause sensitization by inhalation and skin contact . | [Safety Statements ]
S22:Do not breathe dust .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
2
| [RTECS ]
XT5425000
| [HS Code ]
29350090 | [Toxicity]
LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe) |
| Hazard Information | Back Directory | [Uses]
Antibacterial;Inhibitor of folic acid biosynthesis | [storage]
Store at -20°C | [Purification Methods]
Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.] |
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