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ChemicalBook--->CAS DataBase List--->133373-24-7

133373-24-7

133373-24-7 Structure

133373-24-7 Structure
IdentificationMore
[Name]

FMOC-N-ME-TYR(TBU)-OH
[CAS]

133373-24-7
[Synonyms]

FMOC-METYR(TBU)-OH
FMOC-L-METYR(TBU)-OH
FMOC-N-ME-TYR(TBU)-OH
Fmoc-N-Me-L-Tyr(tBu)-OH
FMOC-N-ME-TYR(TBU)-OH 1 G
Fmoc-N-Me-Tyr(tBu)-OH 97%
FMOC-N-ME-TYR(TBU)-OH USP/EP/BP
FMOC-N-METHYL-O-T-BUTYL-L-TYROSINE
FMOC-N-METHYL-O-TERT-BUTYL-L-TYROSINE
N-FMoc-N-Methyl-O-tert-butyl-L-tyrosine
FMOC-N-ALPHA-METHYL-O-T-BUTYL-L-TYROSINE
fMoc-N-Me-tyr(tbu)-oh
Fmoc-N-methyl-O-tert-butyl-L-tyrosine≥ 98% (HPLC)
(9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-Tyr(tBu)-OH
O-(tert-Butyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-tyrosine
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-O-T-BUTYL-L-TYROSINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-O-T-BUTYL-L-TYROSINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-O-TERT-BUTYL-L-TYROSINE
L-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(4-tert-butoxyphenyl)propanoic acid
(2S)-3-[4-(tert-butoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)propanoic acid
[Molecular Formula]

C29H31NO5
[MDL Number]

MFCD02684471
[Molecular Weight]

473.56
[MOL File]

133373-24-7.mol
Chemical PropertiesBack Directory
[Melting point ]

186-191°C
[Boiling point ]

638.9±55.0 °C(Predicted)
[density ]

1.208
[storage temp. ]

Store at 0-5°C
[form ]

powder or crystals
[pka]

2.98±0.10(Predicted)
[optical activity]

[α]22/D -49.0°, c = 0.5% in DMF
[InChIKey]

WTLSDEYZKFJXFT-SANMLTNESA-N
[SMILES]

C(O)(=O)[C@H](CC1=CC=C(OC(C)(C)C)C=C1)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C
[CAS DataBase Reference]

133373-24-7(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

2924 29 70
[HazardClass ]

IRRITANT
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

peptide synthesis
[General Description]

Fmoc-N-Me-Tyr(tBu)-OH is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a very important amino acid - one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
[Synthesis]

(9H-Fluoren-9-yl)methyl carbonochloridate could be used as the starting material to synthesize Fmoc-N-Me-Tyr(tBu)-OH.
Fmoc-N-Me-Tyr(tBu)-OH
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