| Identification | More | [Name]
2-Amino-5,7-dimethoxy-1,2,4-triazolo[1,5-a]pyrimidine | [CAS]
13223-43-3 | [Synonyms]
2-amino-5,7-dimethoxy-1,2,4-triazolo[1,5-a]pyrimidine
5,7-DIMETHOXY-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-AMINE
2-Amino-5,7-Dimethoxy-1,2,4-Triazole-[1,5-A]-Pyrimidine
2-Amino-5,7-Dimethoxy-1,2,4-Tr
[1,2,4]Triazolo[1,5-a]pyrimidin-2-amine,5,7-dimethoxy- | [EINECS(EC#)]
603-562-0 | [Molecular Formula]
C7H9N5O2 | [MDL Number]
MFCD09033220 | [Molecular Weight]
195.18 | [MOL File]
13223-43-3.mol |
| Hazard Information | Back Directory | [Chemical Properties]
White solid | [Uses]
5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine is a useful research chemical compound used in the preparation of N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl) arylsulfonamides as herbicides. | [Synthesis]
The general procedure for the synthesis of 2-amino-5,7-dimethoxy-1,2,4-triazino[1,5-a]pyrimidine from the compound (CAS:102739-44-6) was as follows: 3a (114.5 g, 0.4 mol) and hydroxylamine hydrochloride (40.3 g, 0.58 mol) were dissolved in ethanol (600 mL) and stirred vigorously at 60 °C for 0.5 hours. Subsequently, triethylamine (58.7 g, 0.58 mol) was slowly added dropwise to the reaction mixture. The resulting mixture was refluxed for 5 h. After completion of the reaction, it was cooled to room temperature. The white solid of product 4a was collected by filtration and washed with 200 mL of water to give 71.4 g of product in 91.5% yield. | [References]
[1] Heterocycles, 2016, vol. 92, # 5, p. 829 - 843
[2] Patent: CN105399746, 2016, A. Location in patent: Paragraph 0077-0078
[3] Patent: US2002/111361, 2002, A1 |
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