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ChemicalBook--->CAS DataBase List--->130955-38-3

130955-38-3

130955-38-3 Structure

130955-38-3 Structure
IdentificationBack Directory
[Name]

m-PEG6-Ms
[CAS]

130955-38-3
[Synonyms]

m-PEG6-Ms
2,5,8,11,14-Pentaoxahexadecan-16-ol, 16-methanesulfonate
[Molecular Formula]

C12H26O8S
[MDL Number]

MFCD31693723
[MOL File]

130955-38-3.mol
[Molecular Weight]

330.39
Hazard InformationBack Directory
[Description]

m-PEG6-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. The water solubility properties of the PEG chain are enhanced with longer PEG chains.
[Uses]

m-PEG5-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Cleavable Linker; PEGs
[References]

[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
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