| Identification | More | [Name]
2-Biphenylcarboxaldehyde | [CAS]
1203-68-5 | [Synonyms]
2-BIPHENYLCARBOXALDEHYDE
2-PHENYLBENZALDEHYDE
BIPHENYL-2-CARBALDEHYDE
BIPHENYL-2-CARBOXALDEHYDE
(1,1’-biphenyl)-2-carboxaldehyde
2-difenilaldeide
2-FORMYL-BIPHENYL | [Molecular Formula]
C13H10O | [MDL Number]
MFCD01740431 | [Molecular Weight]
182.22 | [MOL File]
1203-68-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
202 °C | [Boiling point ]
91-92 °C/0.15 mmHg (lit.) | [density ]
1.130 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D >1.6220(lit.)
| [Fp ]
215 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform, Ethyl Acetate | [form ]
Clear Liquid | [InChI]
InChI=1S/C13H10O/c14-10-12-8-4-5-9-13(12)11-6-2-1-3-7-11/h1-10H | [InChIKey]
LCRCBXLHWTVPEQ-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=CC=C2)=CC=CC=C1C=O | [CAS DataBase Reference]
1203-68-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DV1771000
| [HS Code ]
29122990 | [Toxicity]
mouse,LD50,unreported,> 1500mg/kg (1500mg/kg),Farmaco, Edizione Scientifica. Vol. 19, Pg. 964, 1964. |
| Hazard Information | Back Directory | [Chemical Properties]
2-Biphenylcarboxaldehyde is Clear Liquid
| [Uses]
2-Biphenylcarboxaldehyde is a reactant used in the preparation of imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Biphenylcarboxaldehyde is also used in the p reparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin.
| [Synthesis Reference(s)]
The Journal of Organic Chemistry, 54, p. 1523, 1989 DOI: 10.1021/jo00268a009 | [General Description]
Biphenyl-2-carboxaldehyde is an oxygen-containing polycyclic aromatic hydrocarbon derivative (OPAH). It can be prepared via Suzuki cross-coupling reaction between phenyl boronic acid and 2-bromobenzaldehyde. |
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