Identification | Back Directory | [Name]
Aminooxy-PEG3-thiol | [CAS]
1200365-63-4 | [Synonyms]
Aminooxy-PEG3-thiol Aminooxy-PEG3-C2-thiol Aminooxy-PEG3-thiol HCl salt Ethanethiol, 2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]- | [Molecular Formula]
C8H19NO4S | [MDL Number]
MFCD29918250 | [MOL File]
1200365-63-4.mol | [Molecular Weight]
225.31 |
Chemical Properties | Back Directory | [Boiling point ]
349.7±37.0 °C(Predicted) | [density ]
1.105±0.06 g/cm3(Predicted) | [solubility ]
DMSO : 100 mg/mL (443.83 mM; Need ultrasonic) | [form ]
Solid | [pka]
9.65±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
Aminooxy-PEG3-C2-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|