| Identification | Back Directory | [Name]
Ganoderic acid TN | [CAS]
112430-64-5 | [Synonyms]
Ganoderic acid TN
acide ganoderique X
Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3β,15α,24E)-
(3beta,15alpha,24E)-15-(Acetyloxy)-3-hydroxy-lanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oicacid, 15-(acetyloxy)-3-hydroxy-, (3b,15a,24E)- (9CI) | [Molecular Formula]
C32H48O5 | [MDL Number]
MFCD21333654 | [MOL File]
112430-64-5.mol | [Molecular Weight]
512.73 |
| Chemical Properties | Back Directory | [Boiling point ]
625.5±55.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
5.01±0.19(Predicted) |
| Hazard Information | Back Directory | [Description]
23-Dihydroganoderic acid N, a triterpenoid compound, has anticancer effects, shows sensitive to MCF-7 cells among NCI-H460, HeLa, U937, and MCF-7 cells. | [Uses]
Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and?42?μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4?μM)[1]. | [References]
[1] Qinchang Zhu, et al.Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194. DOI:10.1038/srep13194 |
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