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ChemicalBook--->CAS DataBase List--->112430-64-5

112430-64-5

112430-64-5 Structure

112430-64-5 Structure
IdentificationBack Directory
[Name]

Ganoderic acid TN
[CAS]

112430-64-5
[Synonyms]

Ganoderic acid TN
acide ganoderique X
Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3β,15α,24E)-
(3beta,15alpha,24E)-15-(Acetyloxy)-3-hydroxy-lanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oicacid, 15-(acetyloxy)-3-hydroxy-, (3b,15a,24E)- (9CI)
[Molecular Formula]

C32H48O5
[MDL Number]

MFCD21333654
[MOL File]

112430-64-5.mol
[Molecular Weight]

512.73
Chemical PropertiesBack Directory
[Boiling point ]

625.5±55.0 °C(Predicted)
[density ]

1.12±0.1 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

5.01±0.19(Predicted)
Hazard InformationBack Directory
[Description]

23-Dihydroganoderic acid N, a triterpenoid compound, has anticancer effects, shows sensitive to MCF-7 cells among NCI-H460, HeLa, U937, and MCF-7 cells.
[Uses]

Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and?42?μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4?μM)[1].
[References]

[1] Qinchang Zhu, et al.Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194. DOI:10.1038/srep13194
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