| Identification | More | [Name]
2-Methylcyclopentanone | [CAS]
1120-72-5 | [Synonyms]
2-METHYLCYCLOPENTANONE
2-Methylcyclopentan-1-one
2-methyl-cyclopentanon
alpha-Methylcyclopentanone
a-Methylcyclopentanone | [EINECS(EC#)]
214-318-4 | [Molecular Formula]
C6H10O | [MDL Number]
MFCD00001414 | [Molecular Weight]
98.14 | [MOL File]
1120-72-5.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID | [Melting point ]
-75°C | [Boiling point ]
139 °C (lit.) | [density ]
0.917 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.435(lit.)
| [Fp ]
79 °F
| [storage temp. ]
Flammables area | [form ]
Liquid | [color ]
Clear colorless to very slightly yellow | [Water Solubility ]
soluble | [InChI]
InChI=1S/C6H10O/c1-5-3-2-4-6(5)7/h5H,2-4H2,1H3 | [InChIKey]
ZIXLDMFVRPABBX-UHFFFAOYSA-N | [SMILES]
C1(=O)CCCC1C | [LogP]
0.690 (est) | [CAS DataBase Reference]
1120-72-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Cyclopentanone, 2-methyl-(1120-72-5) | [EPA Substance Registry System]
1120-72-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F | [Risk Statements ]
R10:Flammable. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S29:Do not empty into drains .
S33:Take precautionary measures against static discharges . | [RIDADR ]
UN 1224 3/PG 3
| [WGK Germany ]
3
| [HazardClass ]
3.2 | [PackingGroup ]
III | [HS Code ]
29142990 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID | [Uses]
2-Methylcyclopentanone is a useful synthetic intermediate. It was used in the synthesis of MK-0354, a partial agonist of nicotinic acid and G-protein-coupled receptor 109a. It can also be used to prepare Falcipain inhibitors. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 102, p. 190, 1980 DOI: 10.1021/ja00521a031
The Journal of Organic Chemistry, 38, p. 304, 1973 DOI: 10.1021/jo00942a022
Synthetic Communications, 8, p. 563, 1978 DOI: 10.1080/00397917808063587 |
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