| Identification | More | [Name]
2-Hydroxyethylhydrazine | [CAS]
109-84-2 | [Synonyms]
2-HYDRAZINOETHANOL
2-HYDROXYETHYLHYDRAZINE
BETA-HYDROXYETHYL HYDRAZINE
ETHANOL-2-HYDRAZINE
HYDROXYETHYL HYDRAZINE
1-(2-Hydroxyethyl)hydrazine
2-Hydrazineethanol
2-hydrazino-ethano
2-Hydrazinoethyl alcohol
BOH
Brombloom
Ethanol, 2-hydrazino-
Ethanolhydrazine
HEH
Hydrazineethanol
N-(2-Hydroxyethyl)hydrazine
Omaflora
(2-Hydroxyethyl)drazine
2-Hydroxyethylhydrazine,97%
2-HYDROXYETHYLHYDRAZINE, TECH., 90% | [EINECS(EC#)]
203-711-6 | [Molecular Formula]
C2H8N2O | [MDL Number]
MFCD00007623 | [Molecular Weight]
76.1 | [MOL File]
109-84-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless oily liquid | [Melting point ]
−70 °C(lit.) | [Boiling point ]
155-160 °C32 mm Hg(lit.) | [density ]
1.123 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.493(lit.)
| [Fp ]
165 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
soluble in DMSO, Methanol | [form ]
Liquid | [pka]
14.79±0.10(Predicted) | [color ]
Colorless to Almost colorless | [Water Solubility ]
Soluble in water, alcohols and glycols. | [Merck ]
13,4794 | [BRN ]
1731669 | [InChIKey]
GBHCABUWWQUMAJ-UHFFFAOYSA-N | [Uses]
Intermediate, plant growth regulator, flowering
inducer for pineapples. | [CAS DataBase Reference]
109-84-2(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Hydroxyethylhydrazine(109-84-2) | [EPA Substance Registry System]
109-84-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2810 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
KL2800000
| [Hazard Note ]
Toxic | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29280000 |
| Hazard Information | Back Directory | [Hazard]
Moderate fire risk. Irritant. | [Chemical Properties]
Clear colorless oily liquid | [Definition]
ChEBI: 2-hydrazinoethanol is a member of hydrazines. It has a role as a herbicide. It is functionally related to an ethanol. | [Preparation]
2-Hydroxyethylhydrazine is prepared by heating about 2 to 17 parts of hydrazine hydrate dissolved in water to about 30℃ to about 100℃. in a closed system. Then, 1 part of ethylene oxide is gradually added to the hydrazine hydrate, and the temperature of the reaction mixture is maintained in the range of about 30℃ to 70℃ during the addition.
| [General Description]
2-Hydroxyethylhydrazine reacts with β-diketones having strong electron-withdrawing substituents to yield 5-hydroxy-4,5-dihydropyrazoles. | [Synthesis]
The general procedure for synthesizing 2-hydrazinoethanol from ethylene oxide was as follows: ethylene oxide was added to a VO1 liquefied gas storage tank and pressurized to 1.0~1.5 MPa using nitrogen. 80% hydrazine hydrate was added to a VO2 storage tank, and the molar ratio of hydrazine hydrate to ethylene oxide was controlled to be 8:1. the hydrazine hydrate was fed at a total feed flow rate of 2.0 L/h via feed pumps PO1 and PO2, respectively. The temperature of the micro-mixer was maintained at 40°C, the temperature of the cracking reactor was set at 60°C, the temperature of the micro-heat exchanger was controlled in the range of 0-10°C, and the back pressure of the back-pressure valve was set at 1.5-2.5 MPa. The two liquid feedstocks were mixed in a CPMM-R300 micro-mixer and then entered into the cracking reactor for further reaction. The reaction liquid is cooled by a micro heat exchanger and then micro-fed to the receiving vessel. Most of the water and excess hydrazine hydrate were removed by decompression distillation, and the final colorless oily liquid 2-hydroxyethylhydrazine was obtained. The purity of the product was 89.5% and the yield was 98% by GC. Finally, the entire microreactor system was washed using water. | [References]
[1] Patent: CN104876833, 2016, B. Location in patent: Paragraph 0037; 0038
[2] Patent: EP2952509, 2015, A1. Location in patent: Paragraph 0041; 0042
[3] Bulletin de la Societe Chimique de France, 1939, vol. <5> 6, p. 708,714
[4] Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1928, vol. 3, p. 125,128
[5] Chem. Zentralbl., 1930, vol. 101, # I, p. 2867 |
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