午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List (R)-tert-butyl 1-(3-broMophenyl)ethylcarbaMate
1187932-25-7

(R)-tert-butyl 1-(3-broMophenyl)ethylcarbaMate synthesis

1synthesis methods
24424-99-5 Synthesis
Di-tert-butyl dicarbonate

24424-99-5
861 suppliers
$13.50/25G

176707-77-0 Synthesis
(R)-1-(3-Bromophenyl)ethylamine

176707-77-0
93 suppliers
$40.00/1g

-

Yield: 100%

Reaction Conditions:

with triethylamine in dichloromethane at 20;

Steps:

16
Example 16, Compound 16; (E)-(2R,5S,11 S,14S,17R,18R)-11 -(3-Hydroxy-benzyl)-14-isopropyl-18-methoxy- 2,17-dimethyl-3,9,12,15,28-pentaaza-tricyclo[21.3.1.1 *5,9*]octacosa- 1 (27),21 ,23,25-tetraene-4,10,13,16-tetraone.; Com ound 16a: [(R)-1 -(3-Bromo-phenyl)-ethyl]-carbamic acid iert-butyl esterA solution of (R)-bromo-a-methylbenzylamine (1 .023 g, 5.1 12 mmol) indichloromethane (20 mL) was subsequently treated with triethylamine (720 μΙ_, 5.1 12 mmol) and di-te/t-butyl dicarbonate (1 .784 g, 8.179 mmol). After overnight stirring at room temperature, the volatiles were removed in vacuo and the residue was purified by silica gel chromatography using a 50 g Isolute cartridge eluted with a continuous gradient of /so-hexanes/Et20 1 :0 to 4:1 to afford the title compound (1 .552 g, 100%) as a white solid. H NMR (300 MHz, CDCI3) 1 .43 (br s, 12H), 4.77 (br s, 2H), 7.16-7.26 (m, 2H), 7.39 (dt, J = 2.0, 7.1 Hz, 1 H), 7.46 (s, 1 H).

References:

GILEAD SCIENCES, INC.;SELCIA LIMITED;APPLEBY, Todd;FLIRI, Hans, G.;KEATS, Andrew, J.;LAZARIDES, Linos;MACKMAN, Richard, L.;PETTIT, Simon, N.;POULLENNEC, Karine, G.;SANVOISIN, Jonathan;STEADMAN, Victoria, A.;WATT, Gregory, M. WO2012/78915, 2012, A1 Location in patent:Page/Page column 90

(R)-tert-butyl 1-(3-broMophenyl)ethylcarbaMate Related Search: