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144084-34-4

N-(tert-Butyl)-2-chloronicotinamide synthesis

2synthesis methods
2942-59-8 Synthesis
2-Chloronicotinic acid

2942-59-8
827 suppliers
$5.00/25g

N-(tert-Butyl)-2-chloronicotinamide

144084-34-4
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: thionyl chloride / 3 h / Heating
2: pyridine / CHCl3 / 0 - 20 °C

References:

Romero;Morge;Biles;Berrios-Pena;May;Palmer;Johnson;Smith;Busso;Tan;Voorman;Reusser;Althaus;Downey;So;Resnick;Tarpley;Aristoff [Journal of Medicinal Chemistry,1994,vol. 37,# 7,p. 999 - 1014]