ETHYL 3-(2-FURYL)PROPIONATE synthesis
- Product Name:ETHYL 3-(2-FURYL)PROPIONATE
- CAS Number:10031-90-0
- Molecular formula:C9H12O3
- Molecular Weight:168.19
617-88-9
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$250.00/250 mg
105-39-5
416 suppliers
$10.00/5g
10031-90-0
70 suppliers
$30.19/5g
Yield: 89%
Reaction Conditions:
Stage #1:2-Chloromethylfuran with magnesium in diethyl ether at -5; for 1 h;
Stage #2:chloroacetic acid ethyl ester in diethyl ether at 20; for 6 h;
Steps:
1 Example 1; Preparation of condensation products; Preparation of a condensation product of 2-chloromethylfuran and ethyl chloroacetate.
Add 1.16 g to a 100 mL three-necked flask equipped with a reflux condenser and a constant pressure dropping funnel.The substrate was 2-chloromethylfuran, and 20 ml of diethyl ether as a solvent was added.3.6 g of magnesium was added in portions at -5 ° C, and a gas appeared, and the addition was completed.After 1 h of heat preservation reaction, a solution of 1.32 g of ethyl chloroacetate in 10 ml of diethyl ether was added dropwise, and the mixture was added to room temperature for 6 h.After the completion of the reaction, a saturated ammonium chloride solution was added, followed by extraction, liquid separation, and the organic layer was spin-dried to obtain a condensation product.Weighed, the yield was 89%.
References:
University of Science and Technology of China;Fu Yao;Li Xinglong;Xie Guangxia;Chen Shiyan;Kong Qingshan CN109503353, 2019, A Location in patent:Paragraph 0040-0044
623-20-1
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10031-90-0
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623-20-1
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10031-90-0
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98-01-1
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1099-45-2
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10031-90-0
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935-13-7
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10031-90-0
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$30.19/5g