ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE synthesis
- Product Name:ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE
- CAS Number:41248-23-1
- Molecular formula:C8H14O3
- Molecular Weight:158.2
16841-19-3
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64-17-5
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41248-23-1
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$64.00/100mg
Yield:41248-23-1 95%
Reaction Conditions:
with sulfuric acid at 20; for 72 h;
Steps:
Ethyl 1-hydroxycyclopentanecarboxylate
To a solution of 1-hydroxycyclopentanecarboxylic acid (0.98 g, 7.5 mmol) in ethanol (3.8 ml) was added a cat amount of sulfuric acid. The reaction mixture was stuffed for 3 d at room temperature. The solvent was concentrated in vacuo. The residue was partitioned between ethyl acetate (75-ml) and brine (25-ml). The layers were separated. The aqueous layer wasextracted with one 75-ml portion of ethyl acetate. The combined organic layers were dried over anhydrous sodium sulfate and concentrated in vacuo to give the title compound (1.13 g, 95%) as light brown oil. MS mle: 159 ([M+H]j
References:
WO2015/124541,2015,A1 Location in patent:Page/Page column 81
5117-85-1
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41248-23-1
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$64.00/100mg
120-92-3
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$11.00/25g
41248-23-1
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$64.00/100mg
96-41-3
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41248-23-1
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$64.00/100mg