((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER synthesis
- Product Name:((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
- CAS Number:376348-70-8
- Molecular formula:C27H41N5O2
- Molecular Weight:467.65
![3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane-p-toluenesulfonate](/CAS2/GIF/423165-08-6.gif)
423165-08-6
33 suppliers
$188.00/250mg
135865-78-0
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$64.00/100mg
376348-70-8
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Yield:376348-70-8 89%
Reaction Conditions:
with sodium tris(acetoxy)borohydride;acetic acid in 1,2-dichloro-ethane at 0 - 20; for 3 h;Inert atmosphere;
References:
Asano, Shigehiro;Gavrilyuk, Julia;Burton, Dennis R.;Barbas, Carlos F. [ACS Medicinal Chemistry Letters,2014,vol. 5,# 2,p. 133 - 137] Location in patent:supporting information
![(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane](/CAS/GIF/423165-07-5.gif)
423165-07-5
115 suppliers
$60.00/100mg
135865-78-0
96 suppliers
$64.00/100mg
376348-70-8
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190189-97-0
29 suppliers
$400.00/1g
376348-70-8
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76272-34-9
49 suppliers
$140.00/50mg
376348-70-8
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![N-(8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl-exo)-2-methylpropanamide](/CAS2/GIF/376348-67-3.gif)
376348-67-3
62 suppliers
$139.80/10mg
376348-70-8
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