3-PHENYLPROPYL ACETATE synthesis
- Product Name:3-PHENYLPROPYL ACETATE
- CAS Number:122-72-5
- Molecular formula:C11H14O2
- Molecular Weight:178.23
122-97-4
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$6.00/25g
631-61-8
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$11.19/100G
122-72-5
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$11.00/1g
Yield:122-72-5 90%
Reaction Conditions:
with bromine;triphenylphosphine in acetonitrile at 20; for 0.3 h;Reagent/catalyst;Time;
Steps:
Typical procedure for the conversion of 3-phenylpropanol into 3-phenylpropyl acetate using Ph3P/Br2/NH4OAc
General procedure: To a solution of Ph3P(OAc)2, was added 3-phenylpropanol (1 mmol, 0.137 mL). The progress of the reaction was monitored by TLC (Table 3, entry 2). After completion of the reaction (0.3 h) the reaction mixture was filtered to remove the precipitated NH4Br followed by evaporation of the solvent. Column chromatography of the crude mixture on silica gel using n-hexane/EtOAc (3:1) as the eluent gave 3-phenylpropyl acetate in 90% yield (0.159 g).1H NMR (CDCl3, 250 MHz): d 1.88 (q, 2H, J = 7.5 Hz), 1.97 (s, 3H), 2.6 (t, 2H, J = 7.6 Hz), 4.0 (t, 2H, J = 6.5 Hz), 7.0-7.2 (m, 5H). 13C NMR (CDCl3, 62.5 MHz): d 20.9, 30.1, 32.1, 63.8, 126.0, 128.3, 128.4, 141.1, 171.1 ppm.
References:
Iranpoor, Nasser;Firouzabadi, Habib;Elham, Etemadi Davan [Tetrahedron Letters,2013,vol. 54,# 14,p. 1813 - 1816]
103-54-8
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122-72-5
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$11.00/1g
122-97-4
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$6.00/25g
141-78-6
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$20.50/250ml
122-72-5
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$11.00/1g
108-05-4
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$4.00/1000g
122-97-4
405 suppliers
$6.00/25g
122-72-5
125 suppliers
$11.00/1g