5-Aminobenzimidazole synthesis
- Product Name:5-Aminobenzimidazole
- CAS Number:934-22-5
- Molecular formula:C7H7N3
- Molecular Weight:133.15
94-52-0
934-22-5
The general procedure for the synthesis of 5-amino benzimidazole from 5-nitrobenzimidazole was as follows: 5-nitrobenzimidazole (10.0 g, 61.3 mmol) was dissolved in methanol (250 mL) and 10% Pd/C catalyst (0.40 g) was added. The hydrogenation reaction was carried out under atmospheric pressure hydrogen atmosphere for 20 hours. Upon completion of the reaction, the catalyst was removed by Celite filtration. The filtrate was concentrated under reduced pressure to give pure 5-aminobenzimidazole (yield not provided).
94-52-0
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$8.00/5g
934-22-5
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$21.00/1g
Yield:934-22-5 100%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in methanol under 760.051 Torr; for 20 h;
Steps:
10
Example 10; 1H-Benzimidazol-5-amine A solution of 5-nitrobenzin-ddazole (10. 0 g, 61.3 mmol) in methanol (250 mL) was hydrogenated in the presence of 10% Pd/C (0. 40 g) at atmospheric pressure for 20h. The mixture was filtered through CeliteNo. and the solvent removed under reduced pressure to afford the pure product () %).
References:
CYTOPIA RESEARCH PTY LTD WO2005/66156, 2005, A1 Location in patent:Page/Page column 33
99-56-9
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$6.00/5g
934-22-5
174 suppliers
$21.00/1g
51-17-2
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$14.00/25g
934-22-5
174 suppliers
$21.00/1g
95-54-5
542 suppliers
$9.00/1g
934-22-5
174 suppliers
$21.00/1g