Quinoline, 4-chloro-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]- synthesis
- Product Name:Quinoline, 4-chloro-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-
- CAS Number:1061610-61-4
- Molecular formula:C18H24ClN3O2
- Molecular Weight:349.86
498-02-2
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1061610-61-4
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Yield:-
Steps:
Multi-step reaction with 6 steps
1: potassium carbonate / acetone / 20 - 25 °C
2: nitric acid / dichloromethane / 4 h / 0 °C
3: toluene / 10 h / 110 °C
4: iron; acetic acid / 2 h / 60 - 80 °C
5: acetonitrile / 10 h / 85 °C
6: trichlorophosphate / acetonitrile / 6 h / 85 °C
References:
Li, Sai;Jiang, Rui;Qin, Mingze;Liu, Haicheng;Zhang, Guangyan;Gong, Ping [Archiv der Pharmazie,2013,vol. 346,# 7,p. 521 - 533]
58113-30-7
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1160707-44-7
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1061610-61-4
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1428788-16-2
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1061610-61-4
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