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ACS Applied Materials & Interfaces

ACS Applied Materials & Interfaces

IF: 8.3
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Antibacterial Soy Protein Isolate Prepared by Quaternization.

Published:14 August 2022 DOI: 10.3390/ijms23169110 PMID: 36012376
Qi Dong, Jingwen Lei, Hanjian Wang, Meifang Ke, Xiao Liang, Xindi Yang, Hui Liang, Céline Huselstein, Zan Tong, Yun Chen

Abstract

Soy protein isolate (SPI) is green, high-yield natural plant protein, which is widely applied in industry (packing material and adhesives) and tissue engineering. It is meaningful to improve the antibacterial property of soy protein isolate to fabricate versatile safe products to meet people's requirements. In this study, quaternized soy protein isolate (QSPI) was synthesized by the reaction between 2,3-epoxypropyltrimethylammonium chloride (EPTMAC) and SPI. The positive charged (17.8 ± 0.23 mV) quaternary ammonium groups endow the QSPI with superior antibacterial properties against multiple bacteria in vitro and in vivo. Notably, QSPI maintains its good biocompatibility and promotes bacterial-infected wound healing in rat models. Furthermore, QSPI possesses superior water solubility in a broad pH range than raw SPI. Altogether, this soy protein isolate derivative with antibacterial property and superior water solubility may extend the application of SPI in industry and tissue engineering.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
2,3-Epoxypropyltrimethylammonium chloride 3033-77-0 C6H14ClNO 276 suppliers $5.00-$4177.06
Soy protein isolate 9010-10-0 C13H10N2 221 suppliers Inquiry
Isolated Soy Protein 56 suppliers Inquiry

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