產(chǎn)品概述
MMP8 (4B14) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,IP,IF-P
Human,Mouse,Rat
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
MMP8
HNC; CLG1; MMP-8; PMNL-CL; COLLAGENASE I; NEUTROPHIL; matrix metalloproteinase 8;
4317
P22894
產(chǎn)品應(yīng)用
WB 1:1000-1:5000, IHC-P/IF-P 1:100-1:200, IP 1:50
53kDa
研究背景
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Can degrade fibrillar type I, II, and III collagens.
研究領(lǐng)域
武漢恩璣生命科技有限公司
聯(lián)系商家時(shí)請(qǐng)?zhí)峒癱hemicalbook,有助于交易順利完成!
吳經(jīng)理