產品概述
Phospho-EGFR (Tyr1092) Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC-P
Human,Mouse,Rat
產品性能
Unconjugated
Phosphorylated
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
EGFR
EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
1956
P00533
產品應用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 134 kDa; Observed MW: 175 kDa
研究背景
EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
研究領域
Signal Transduction
武漢恩璣生命科技有限公司
聯(lián)系商家時請?zhí)峒癱hemicalbook,有助于交易順利完成!
在線客服