產(chǎn)品概述
Phospho-ATP Citrate Synthase (Thr447/Ser451) Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human
產(chǎn)品性能
Unconjugated
Phosphorylated
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
ACLY
ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme
47
P53396
產(chǎn)品應(yīng)用
WB: 1:500-1:1000
Calculated MW: 121 kDa; Observed MW: 121 kDa
研究背景
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
研究領(lǐng)域
Signal Transduction
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