產(chǎn)品概述
PPP4C Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human,Mouse,Rat
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
PPP4C
PP4; PPX; PP4C; PPH3; PPP4
5531
P60510
產(chǎn)品應(yīng)用
WB: 1:500-1:1000
Calculated MW: 35 kDa; Observed MW: 35 kDa
研究背景
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.
研究領(lǐng)域
Signal Transduction
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