產(chǎn)品概述
CD31 (2D3) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IP
Human
產(chǎn)品性能
Unconjugated
Unmodified
IgG1
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
PECAM1
Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31
5175
P16284
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 83 kDa; Observed MW: 130 kDa
研究背景
PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
研究領(lǐng)域
Cardiovascular
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