Product Name：BOC-Dap-NE
CAS No.： 160800-65-7
Synonyms：抗體-藥物偶聯(lián)物（ADC）關(guān)鍵連接物
Catalog No.：220P177
Brand：Typeptide Biotech（肽研生物）
Description：BOC-Dap-NE 作為連接物，可幫助抗體選擇性地將細(xì)胞毒性藥物傳遞到腫瘤細(xì)胞中，并在腫瘤部位準(zhǔn)確釋放，從而發(fā)揮抗癌作用。此外，BOC-Dap-NE還是合成 Monomethyl auristatin E 的中間體，后者是微管蛋白聚合抑制劑，可作為毒素用于合成 ADC。
BOC-Dap-NE as a linker, can help antibodies selectively deliver cytotoxic drugs to tumor cells and accurately release them at the tumor site, thereby exerting anti-cancer effects. In addition, BOC Dap NE is also an intermediate for the synthesis of monomethyl auristatin E, which is a microtubule polymerization inhibitor and can be used as a toxin for the synthesis of ADCs.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | BOC-Dap-NE |
Sequence(3-letter code) | tert-butyl (2R)-2-((2S)-3-(((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate |
Peptide Structure | 
|
Molecular Formula | C23H36N2O5 |
Molecular Weight | 420.54 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： BOC-Dap-NE;抗體-藥物偶聯(lián)物（ADC）關(guān)鍵連接物;160800-65-7;小分子;多肽小分子;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。