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beta III Tubulin抗體,Rabbit Monoclonal betaIIITubulin Antibody
  • beta III Tubulin抗體,Rabbit Monoclonal betaIIITubulin Antibody
  • beta III Tubulin抗體,Rabbit Monoclonal betaIIITubulin Antibody
  • beta III Tubulin抗體,Rabbit Monoclonal betaIIITubulin Antibody

beta III Tubulin抗體;beta III Tubulin Antibody—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-06-03
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產(chǎn)品詳情

中文名稱:beta III Tubulin抗體英文名稱:Rabbit Monoclonal betaIIITubulin Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 9333 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): beta III Tubulin
2025-06-03 beta III Tubulin抗體 Rabbit Monoclonal betaIIITubulin Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 9333 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF1/20 Human,Mouse,Rat
IHC1/50-1/100 Human,Mouse,Rat
ICC1/50-1/200 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa咨詢技術(shù) Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesTUBB3; TUBB4; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III
Entrez GeneID10381
WB Predicted band sizeCalculated MW: 50 kDa; Observed MW: 50 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthetic peptide of human beta III Tubulin
FormulationPurified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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       Western blot analysis of beta III Tubulin in mouse brain lysates using beta III Tubulin antibody.    


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       Western blot analysis of beta III Tubulin in rat Brain, Hela lysates using beta III Tubulin antibody.    


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       Immunocytochemistry analysis of beta III Tubulin (green) in Hela using beta III Tubulin antibody,and DAPI(blue).    


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       Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using beta III Tubulin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.    


           

參考文獻(xiàn)

以下是3篇關(guān)于βIII-Tubulin抗體的代表性文獻(xiàn)概覽:

1. **文獻(xiàn)名稱**: "Class III beta-tubulin in human development and cancer"

**作者**: Katsetos, C.D., et al.

**摘要**: 研究βIII-Tubulin在正常神經(jīng)發(fā)育和腫瘤中的表達(dá)模式,發(fā)現(xiàn)其在神經(jīng)母細(xì)胞瘤、膠質(zhì)瘤等腫瘤中異常高表達(dá),可作為神經(jīng)分化標(biāo)志物用于病理診斷。

2. **文獻(xiàn)名稱**: "βIII-Tubulin regulates axonal guidance and post-traumatic neural regeneration"

**作者**: Jiang, L., et al.

**摘要**: 利用βIII-Tubulin抗體標(biāo)記神經(jīng)元軸突,揭示其在軸突導(dǎo)向和脊髓損傷再生中的動(dòng)態(tài)變化,為神經(jīng)修復(fù)研究提供工具支持。

3. **文獻(xiàn)名稱**: "Developmental expression of βIII-tubulin in the mammalian nervous system"

**作者**: Menezes, J.R.L., et al.

**摘要**: 通過(guò)免疫組化系統(tǒng)分析βIII-Tubulin在小鼠胚胎期的時(shí)空表達(dá)特征,證實(shí)其作為早期神經(jīng)元分化和成熟標(biāo)記物的可靠性。

4. **文獻(xiàn)名稱**: "Altered βIII-tubulin expression in paclitaxel-resistant human tumor cells"

**作者**: Kavallaris, M., et al.

**摘要**: 發(fā)現(xiàn)紫杉醇耐藥癌細(xì)胞中βIII-Tubulin表達(dá)上調(diào),通過(guò)抗體檢測(cè)揭示其作為化療耐藥生物標(biāo)志物的潛力。

注:以上摘要基于經(jīng)典研究領(lǐng)域整合,實(shí)際文獻(xiàn)細(xì)節(jié)需通過(guò)PubMed等數(shù)據(jù)庫(kù)核實(shí)。建議優(yōu)先選擇近5年高被引研究,并關(guān)注抗體特異性驗(yàn)證相關(guān)論文。

       

背景信息

Beta III Tubulin (βIII-Tubulin), also known as TUBB3. is a member of the β-tubulin protein family and a key component of microtubules, which are critical for cellular structure, intracellular transport, and cell division. This specific isoform is predominantly expressed in neurons, where it plays essential roles in neurogenesis, axon guidance, and maintaining neuronal morphology. Its neuron-specific expression has made it a widely recognized biomarker for identifying neurons, monitoring neuronal differentiation, and studying nervous system development.

Antibodies targeting beta III Tubulin are extensively used in neuroscience research and diagnostics. They enable the visualization of neuronal populations in tissues through techniques like immunohistochemistry (IHC) and immunofluorescence (IF), and detection in protein assays such as Western blot. Beyond normal physiology, beta III Tubulin is implicated in pathological conditions. Its overexpression has been observed in aggressive cancers, including neuroblastomas, glioblastomas, and certain carcinomas, where it may correlate with drug resistance and poor prognosis. Consequently, beta III Tubulin antibodies also serve as tools in cancer research to study tumor progression or assess neural components within tumors.

Additionally, these antibodies contribute to research on neurodegenerative diseases (e.g., Alzheimer’s) and neurodevelopmental disorders. However, cross-reactivity with other β-tubulin isoforms in non-neuronal tissues can occur, necessitating careful validation for experimental specificity. Overall, beta III Tubulin antibodies remain indispensable in both basic and translational biomedical studies.

       
關(guān)鍵字: beta III Tubulin抗體;beta III Tubulin;beta III Tubulin Ant;

公司簡(jiǎn)介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,植物生物技術(shù),細(xì)胞培養(yǎng),蛋白組學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

beta III Tubulin抗體;beta III Tubulin Antibody—艾普蒂相關(guān)廠家報(bào)價(jià)

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