The 45566 antibody is a monoclonal antibody commonly utilized in biomedical research for detecting specific protein targets. While detailed commercial information may vary by manufacturer, antibodies labeled with this catalog number typically target intracellular or cell surface antigens involved in critical cellular processes such as signaling pathways, immune regulation, or disease mechanisms. For instance, some 45566 clones may recognize epitopes on proteins associated with cancer progression, neurodegenerative disorders, or inflammatory responses.
Developed in murine or rabbit host systems, these antibodies are often validated for applications like Western blotting (WB), immunohistochemistry (IHC), or flow cytometry. Their specificity is generally confirmed through knockout/knockdown controls or peptide blocking assays. Researchers frequently employ 45566 antibodies to investigate protein expression patterns, subcellular localization, or functional interactions in disease models.
The target antigen’s biological significance often dictates its research relevance. If the antibody binds to a kinase or receptor, for example, it might be used to study therapeutic target modulation. Commercial suppliers typically provide technical data sheets outlining recommended dilutions, buffer conditions, and species reactivity (e.g., human, mouse). As with many research antibodies, batch variability and independent validation remain considerations for experimental reproducibility. Users are advised to consult manufacturer documentation and cite catalog numbers in publications for traceability.