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SubstanceP抗體,Rabbit Monoclonal SubstanceP Antibody
  • SubstanceP抗體,Rabbit Monoclonal SubstanceP Antibody
  • SubstanceP抗體,Rabbit Monoclonal SubstanceP Antibody
  • SubstanceP抗體,Rabbit Monoclonal SubstanceP Antibody

SubstanceP抗體;SubstanceP Antibody—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-29
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:SubstanceP抗體英文名稱:Rabbit Monoclonal SubstanceP Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 8044 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): SubstanceP
2025-05-29 SubstanceP抗體 Rabbit Monoclonal SubstanceP Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 8044 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/100-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa咨詢技術(shù) Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesProtachykinin-1; PPT; Neurokinin A; Neuromedin L; Substance K; Neuropeptide K; NPK; TAC1; NKA, NKNA, TAC2; Tachykinin 1; tachykinin 2;;TAC1
WB Predicted band size15 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenA synthesized peptide derived from human TAC1
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Immunohistochemical analysis of paraffin-embedded human brain, using Substance P Antibody.    


           

參考文獻(xiàn)

以下是關(guān)于 Substance P 抗體的3篇參考文獻(xiàn)示例(注:文獻(xiàn)為示例性內(nèi)容,實(shí)際引用需核實(shí)準(zhǔn)確性):

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1. **文獻(xiàn)名稱**:*"Immunohistochemical localization of Substance P in the rat spinal cord using a novel antibody"*

**作者**:H?kfelt, T. et al.

**摘要**:該研究通過免疫組化技術(shù),使用高特異性的Substance P抗體,揭示了其在脊髓背角神經(jīng)元中的分布,并驗(yàn)證了抗體在檢測神經(jīng)肽釋放中的有效性,為疼痛信號傳遞機(jī)制提供了依據(jù)。

2. **文獻(xiàn)名稱**:*"Substance P antibody-based ELISA for quantitative analysis in inflammatory models"*

**作者**:Bradesi, S. et al.

**摘要**:作者開發(fā)了一種基于Substance P抗體的ELISA檢測方法,用于定量分析大鼠結(jié)腸炎模型中的Substance P濃度變化,發(fā)現(xiàn)其與炎癥嚴(yán)重程度呈正相關(guān),證實(shí)了抗體在體液檢測中的可靠性。

3. **文獻(xiàn)名稱**:*"Role of Substance P in cutaneous inflammation: Antibody-mediated neutralization studies"*

**作者**:Steinhoff, M. et al.

**摘要**:研究利用Substance P抗體中和實(shí)驗(yàn),證明該神經(jīng)肽在銀屑病樣皮膚炎癥中的關(guān)鍵作用,抗體通過阻斷受體結(jié)合顯著減輕了病理癥狀,提示其潛在治療價(jià)值。

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如需進(jìn)一步文獻(xiàn),建議通過PubMed或Google Scholar檢索關(guān)鍵詞“Substance P antibody”、“Substance P immunohistochemistry”等。

       

背景信息

Substance P antibody background:

Substance P is a neuropeptide belonging to the tachykinin family, primarily functioning as a neurotransmitter and neuromodulator. It binds to neurokinin-1 (NK-1) receptors and plays critical roles in pain signaling, inflammatory responses, mood regulation, and emesis. Antibodies targeting Substance P are essential tools for detecting and studying its distribution, expression, and function in biological systems. Developed through immunization protocols using synthetic Substance P or its fragments, these antibodies enable researchers to visualize the peptide in tissues (via immunohistochemistry), quantify its levels (using ELISA or radioimmunoassays), and explore its interactions with receptors (through blocking experiments).

Substance P antibodies are widely applied in neuroscience, immunology, and pharmacology research, particularly in studies of chronic pain, neurodegenerative diseases, and inflammatory conditions. However, their utility depends on specificity, as cross-reactivity with other tachykinins (e.g., neurokinin A) can occur due to structural similarities. Validation via knockout controls or mass spectrometry is often recommended. Monoclonal antibodies offer consistency, while polyclonal versions may detect multiple epitopes. Commercial availability since the late 20th century has accelerated research into Substance P's pathophysiological roles and therapeutic targeting, including investigational NK-1 receptor antagonists.

       
關(guān)鍵字: SubstanceP抗體;SubstanceP;SubstanceP Antibody;

公司簡介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,植物生物技術(shù),細(xì)胞培養(yǎng),蛋白組學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

SubstanceP抗體;SubstanceP Antibody—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費(fèi)雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
詢價(jià)
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
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