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BRAP抗體,Mouse Monoclonal BRAP Antibody
  • BRAP抗體,Mouse Monoclonal BRAP Antibody
  • BRAP抗體,Mouse Monoclonal BRAP Antibody
  • BRAP抗體,Mouse Monoclonal BRAP Antibody

BRAP抗體;BRAP Antibody—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-29
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:BRAP抗體英文名稱:Mouse Monoclonal BRAP Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 7634 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Mouse
偶聯(lián)物: 靶點: BRAP
2025-05-29 BRAP抗體 Mouse Monoclonal BRAP Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 7634 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/100-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa咨詢技術(shù) Human,Mouse,Rat
   

產(chǎn)品詳情

Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human BRAP
FormulationPurified antibody in PBS with 0.05% sodium azide

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       IHC-P analysis of testis tissue by BRAP antibody (P15728) IHC-P was performed using sections of the formalin-fixed paraffin-embedded testis tissue;Result: Cells in seminiferous ducts are positively stained at the cytoplasm.    


           

參考文獻

以下是基于BRAP(BRCA1關(guān)聯(lián)蛋白)相關(guān)研究的示例性參考文獻,供參考。請注意,這些為模擬示例,建議通過學(xué)術(shù)數(shù)據(jù)庫(如PubMed、Google Scholar)檢索最新文獻:

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1. **文獻名稱**:*"BRAP functions as a cytoplasmic retention protein for BRCA1 in DNA damage repair"*

**作者**:Li, H., et al.

**摘要**:研究揭示了BRAP通過調(diào)控BRCA1的細胞質(zhì)定位影響DNA損傷修復(fù)過程,開發(fā)的BRAP抗體證實其在乳腺癌細胞中與BRCA1的相互作用,為靶向治療提供新思路。

2. **文獻名稱**:*"Development of a monoclonal antibody against BRAP for immunohistochemical analysis in hepatocellular carcinoma"*

**作者**:Yamamoto, S., et al.

**摘要**:報道了一種高特異性BRAP單克隆抗體的開發(fā),并用于肝細胞癌組織檢測,發(fā)現(xiàn)BRAP高表達與患者預(yù)后不良相關(guān),提示其作為潛在生物標志物的價值。

3. **文獻名稱**:*"BRAP modulates NF-κB signaling via ubiquitination pathways: Insights from knockdown and antibody-based inhibition studies"*

**作者**:Chen, J., & Wang, Q.

**摘要**:通過BRAP抗體阻斷實驗,證明BRAP通過泛素化修飾調(diào)控NF-κB信號通路,影響炎癥反應(yīng)和腫瘤發(fā)生,為慢性炎癥疾病機制研究提供依據(jù)。

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**建議**:BRAP相關(guān)研究相對較少,建議結(jié)合具體研究背景(如癌癥類型、信號通路)擴展關(guān)鍵詞,或在數(shù)據(jù)庫中檢索“BRAP antibody”及其別名(如BRCA1-associated protein antibody)。

       

背景信息

BRAP (BRCA1-associated protein) antibodies are essential tools in studying the role of BRAP in cellular processes and disease mechanisms. BRAP, also known as BRCA1-associated protein 2 (BRAP2), interacts with BRCA1. a tumor suppressor protein critical for DNA repair, genomic stability, and cell cycle regulation. This interaction links BRAP to pathways involved in maintaining genomic integrity, particularly in response to DNA damage. Dysregulation of BRAP has been implicated in cancer, especially breast and ovarian cancers, where BRCA1 mutations are common. BRAP antibodies enable researchers to detect and quantify BRAP expression in tissues or cell lines, facilitating investigations into its functional roles, protein-protein interactions, and post-translational modifications. They are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Additionally, BRAP antibodies aid in exploring its potential as a biomarker for cancer prognosis or therapeutic targeting. Recent studies also suggest BRAP involvement in inflammatory and metabolic pathways, expanding its relevance beyond oncology. However, challenges remain in ensuring antibody specificity and reproducibility across experimental models. Continued research using BRAP antibodies may uncover novel mechanisms underlying DNA repair, carcinogenesis, and therapeutic resistance, offering insights for precision medicine strategies.
       
關(guān)鍵字: BRAP抗體;BRAP;BRAP Antibody;

公司簡介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,植物生物技術(shù),細胞培養(yǎng),蛋白組學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

BRAP抗體;BRAP Antibody—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
詢價
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
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