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NIPSNAP1抗體,Rabbit Polyclonal NIPSNAP1 Antibody
  • NIPSNAP1抗體,Rabbit Polyclonal NIPSNAP1 Antibody
  • NIPSNAP1抗體,Rabbit Polyclonal NIPSNAP1 Antibody
  • NIPSNAP1抗體,Rabbit Polyclonal NIPSNAP1 Antibody

NIPSNAP1抗體;NIPSNAP1 Antibody—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-28
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:NIPSNAP1抗體英文名稱:Rabbit Polyclonal NIPSNAP1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 7436 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: NIPSNAP1
2025-05-28 NIPSNAP1抗體 Rabbit Polyclonal NIPSNAP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 7436 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/30-1/150 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human NIPSNAP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13692(NIPSNAP1 Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P13692(NIPSNAP1 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NIPSNAP1抗體的3篇參考文獻(xiàn)及其簡要摘要:

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1. **文獻(xiàn)名稱**:*NIPSNAP1 regulates mitochondrial homeostasis through mitophagy*

**作者**:Smith J, Doe R, Lee S. et al.

**摘要**:該研究揭示了NIPSNAP1蛋白通過調(diào)控線粒體自噬(mitophagy)維持線粒體穩(wěn)態(tài)的機制,利用特異性抗體證實其在帕金森病模型中與PINK1/Parkin通路的相互作用,為神經(jīng)退行性疾病提供了潛在治療靶點。

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2. **文獻(xiàn)名稱**:*NIPSNAP1 as a biomarker for colorectal cancer progression*

**作者**:Chen L, Wang X, Zhang Y.

**摘要**:通過免疫組化(IHC)和Western blot分析,研究者發(fā)現(xiàn)NIPSNAP1在結(jié)直腸癌組織中高表達(dá),其抗體檢測顯示其表達(dá)水平與腫瘤侵襲性及患者預(yù)后顯著相關(guān),提示其作為癌癥診斷標(biāo)志物的潛力。

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3. **文獻(xiàn)名稱**:*NIPSNAP1 interacts with vesicular trafficking proteins in neuronal development*

**作者**:Garcia M, Patel K, Kim H.

**摘要**:該研究利用NIPSNAP1抗體進(jìn)行共聚焦顯微鏡和免疫共沉淀(Co-IP)實驗,證明其在神經(jīng)元發(fā)育過程中與突觸囊泡運輸?shù)鞍?如Synaptotagmin)存在功能關(guān)聯(lián),可能影響突觸傳遞和神經(jīng)回路形成。

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注:以上文獻(xiàn)為示例性質(zhì),實際引用需根據(jù)具體研究補充完整信息。

       

背景信息

The NIPSNAP1 antibody is a tool used to detect the NIPSNAP1 protein, a member of the "nipsnap" (4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein) family. NIPSNAP1 is a highly conserved mitochondrial protein implicated in mitochondrial quality control, autophagy (mitophagy), and cellular energy metabolism. Studies suggest it acts as a mitochondrial surveillance factor, recruiting autophagy machinery to damaged mitochondria by interacting with proteins like Parkin and PINK1. which are critical in Parkinson’s disease pathways. Dysregulation of NIPSNAP1 has been linked to neurodegenerative disorders (e.g., Parkinson’s, Alzheimer’s) and cancers (e.g., colorectal, breast), where altered mitochondrial function contributes to disease progression.

NIPSNAP1 antibodies are widely used in research to study protein expression, localization, and interactions via techniques like Western blotting, immunofluorescence, and immunohistochemistry. They help elucidate its role in mitochondrial dynamics, stress responses, and disease mechanisms. Commercial antibodies are typically validated for specificity in human, mouse, or rat models. Recent research also explores NIPSNAP1’s potential as a biomarker or therapeutic target, emphasizing its importance in understanding mitochondrial dysfunction-related pathologies. Despite progress, its exact molecular mechanisms remain under investigation, driving ongoing demand for reliable antibodies to support mechanistic and translational studies.

       
關(guān)鍵字: NIPSNAP1抗體;NIPSNAP1;NIPSNAP1 Antibody;

公司簡介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,植物生物技術(shù),細(xì)胞培養(yǎng),蛋白組學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

NIPSNAP1抗體;NIPSNAP1 Antibody—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥1950
VIP3年
上海滬震實業(yè)有限公司
2025-08-01
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
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