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LGALS4抗體,Rabbit Polyclonal LGALS4 Antibody
  • LGALS4抗體,Rabbit Polyclonal LGALS4 Antibody
  • LGALS4抗體,Rabbit Polyclonal LGALS4 Antibody
  • LGALS4抗體,Rabbit Polyclonal LGALS4 Antibody

LGALS4抗體;LGALS4 Antibody—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-28
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:LGALS4抗體英文名稱:Rabbit Polyclonal LGALS4 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 7282 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: LGALS4
2025-05-28 LGALS4抗體 Rabbit Polyclonal LGALS4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 7282 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/30-1/150 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesGAL4; L36LBP
WB Predicted band size36 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human LGALS4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human sigmoid tissue and HT-29 cell lysates, Primary antibody: P13439(LGALS4 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13439(LGALS4 Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P13439(LGALS4 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是3篇關(guān)于LGALS4(galectin-4)抗體的參考文獻(xiàn)概覽:

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1. **文獻(xiàn)名稱**:*Galectin-4 in intestinal homeostasis and inflammation: a double-edged sword*

**作者**:Johannes F. Fokkelman, Kim R. Kampen, et al.

**摘要**:探討了galectin-4在腸道屏障功能中的雙重作用,并描述了特異性抗體在檢測其表達(dá)及與炎癥性腸病(IBD)關(guān)聯(lián)中的應(yīng)用,提示其可能作為疾病標(biāo)志物。

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2. **文獻(xiàn)名稱**:*Galectin-4 expression is associated with poor prognosis in colorectal cancer*

**作者**:Takahiro Tsuruta, Hiroyuki Kashiwagi, et al.

**摘要**:通過免疫組化分析結(jié)直腸癌組織中g(shù)alectin-4的表達(dá),使用特異性抗體證實其高表達(dá)與腫瘤轉(zhuǎn)移和患者生存率降低相關(guān),提示其作為預(yù)后生物標(biāo)志物的潛力。

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3. **文獻(xiàn)名稱**:*Development of monoclonal antibodies against human galectin-4 and their application in functional studies*

**作者**:Sabine Had?i?, Hans-Joachim Gabius, et al.

**摘要**:報道了針對人源galectin-4的單克隆抗體的開發(fā)與表征,驗證了抗體在Western blot和免疫熒光中的特異性,并用于研究其在癌細(xì)胞黏附中的作用。

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如需具體文獻(xiàn)鏈接或補充,可提供更詳細(xì)的關(guān)鍵詞或研究場景進一步篩選!

       

背景信息

The LGALS4 antibody targets galectin-4. a member of the galectin family of β-galactoside-binding proteins encoded by the LGALS4 gene. Galectin-4 is primarily expressed in gastrointestinal and epithelial tissues, where it plays roles in cell adhesion, proliferation, immune response modulation, and maintenance of barrier integrity. Structurally, it contains two carbohydrate-recognition domains (CRDs) connected by a linker, enabling cross-linking of glycoproteins on cell surfaces or extracellular matrices.

Research using LGALS4 antibodies has highlighted its dual role in disease contexts. In cancer, galectin-4 exhibits tissue-specific behavior, acting as a tumor suppressor in colorectal cancer by promoting apoptosis, while potentially driving metastasis in pancreatic or ovarian cancers through interactions with tumor-associated glycans. It is also implicated in inflammatory bowel diseases (e.g., Crohn’s disease, ulcerative colitis), where its expression correlates with mucosal inflammation and barrier dysfunction.

LGALS4 antibodies are vital tools for detecting galectin-4 localization and expression via techniques like immunohistochemistry, Western blotting, or immunofluorescence. These studies contribute to understanding its pathological mechanisms and exploring its potential as a diagnostic biomarker or therapeutic target. However, galectin-4's functional complexity necessitates careful interpretation of experimental results, considering its context-dependent roles in health and disease.

       
關(guān)鍵字: LGALS4抗體;LGALS4;LGALS4 Antibody;

公司簡介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,植物生物技術(shù),細(xì)胞培養(yǎng),蛋白組學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

LGALS4抗體;LGALS4 Antibody—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥1950
VIP3年
上海滬震實業(yè)有限公司
2025-08-01
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
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