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DHRS4抗體,Rabbit Polyclonal DHRS4 Antibody
  • DHRS4抗體,Rabbit Polyclonal DHRS4 Antibody
  • DHRS4抗體,Rabbit Polyclonal DHRS4 Antibody
  • DHRS4抗體,Rabbit Polyclonal DHRS4 Antibody

DHRS4抗體;DHRS4 Antibody—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-28
QQ交談 微信洽談

產品詳情

中文名稱:DHRS4抗體英文名稱:Rabbit Polyclonal DHRS4 Antibody
品牌: 艾普蒂產地: 武漢
保存條件: Stored at -20°C for 7168 year. Avoid repeated freeze / thaw cycles.產品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯物: 靶點: DHRS4
2025-05-28 DHRS4抗體 Rabbit Polyclonal DHRS4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 7168 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產品詳情

AliasesCR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human DHRS4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13264(DHRS4 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P13264(DHRS4 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻

以下是關于DHRS4抗體的3篇示例參考文獻(內容為模擬概括,僅供參考):

1. **文獻名稱**: "DHRS4 functions as a tumor suppressor in hepatocellular carcinoma via regulating retinoic acid signaling"

**作者**: Li X, Wang Y, Chen J

**摘要**: 本研究利用DHRS4特異性抗體,通過免疫組化和Western blot技術,發(fā)現DHRS4在肝癌組織中表達顯著下調。實驗表明,DHRS4通過調控視黃酸代謝通路抑制腫瘤細胞增殖,提示其作為肝癌潛在治療靶點。

2. **文獻名稱**: "Epigenetic silencing of DHRS4 promotes colorectal cancer progression by activating Wnt/β-catenin pathway"

**作者**: Zhang H, Liu R, Guo M

**摘要**: 文章通過DHRS4抗體檢測結直腸癌樣本中的蛋白表達水平,結合甲基化分析,揭示DHRS4因啟動子高甲基化而表達沉默。功能實驗證實其缺失通過激活Wnt通路促進腫瘤侵襲,抗體驗證為關鍵實驗手段。

3. **文獻名稱**: "Characterization of a novel monoclonal antibody against human DHRS4 for metabolic studies"

**作者**: Smith KA, Johnson TL, Brown P

**摘要**: 本研究報道了一種針對人DHRS4蛋白的單克隆抗體的開發(fā)與驗證。通過免疫沉淀和免疫熒光技術驗證抗體特異性,并應用于肝臟和腎臟組織代謝研究,證明DHRS4在脂類代謝中的重要作用。

**提示**:以上為示例文獻,實際文獻需通過PubMed/Google Scholar等平臺以“DHRS4 antibody”或“DHRS4 function”為關鍵詞檢索。建議結合研究領域(如癌癥、代謝疾病)進一步篩選。

       

背景信息

The DHRS4 (short-chain dehydrogenase/reductase family member 4) antibody is a tool used to detect and study the DHRS4 protein, which belongs to the short-chain dehydrogenase/reductase (SDR) superfamily. DHRS4 is implicated in various metabolic pathways, including steroid hormone biosynthesis, retinoid metabolism, and detoxification processes. The protein functions as an NADPH-dependent reductase, catalyzing the conversion of carbonyl compounds to their corresponding alcohols. It is encoded by the DHRS4 gene located on human chromosome 1 (1p36.22) and is expressed in multiple tissues, such as the liver, kidney, and brain.

DHRS4 has garnered interest due to its evolutionary conservation and the presence of two pseudogenes (DHRS4L1 and DHRS4L2) in its genomic locus, which may influence its regulation. Studies suggest its involvement in cellular redox homeostasis and potential roles in cancer, neurodegenerative diseases, and metabolic disorders. The DHRS4 antibody is commonly used in applications like Western blotting, immunohistochemistry, and immunofluorescence to localize and quantify the protein in biological samples. Researchers also utilize it to explore DHRS4's interactions with substrates or binding partners, its tissue-specific expression patterns, and its regulatory mechanisms under stress or disease conditions. Validation of the antibody typically includes knockout controls or knockdown experiments to confirm specificity. Its development aids in elucidating DHRS4's physiological functions and its relevance to human health.

       
關鍵字: DHRS4抗體;DHRS4;DHRS4 Antibody;

公司簡介

生物技術有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數 1-10人 年營業(yè)額 ¥ 100萬以內
主營行業(yè) 抗體,植物生物技術,細胞培養(yǎng),蛋白組學 經營模式 貿易,工廠,試劑,定制,服務
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產品:生物試劑
  • 公司地址:青浦
詢盤

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