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TBX3抗體,Rabbit Polyclonal TBX3 Antibody
  • TBX3抗體,Rabbit Polyclonal TBX3 Antibody
  • TBX3抗體,Rabbit Polyclonal TBX3 Antibody
  • TBX3抗體,Rabbit Polyclonal TBX3 Antibody

TBX3抗體;TBX3 Antibody—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-26
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:TBX3抗體英文名稱:Rabbit Polyclonal TBX3 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 6761 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): TBX3
2025-05-26 TBX3抗體 Rabbit Polyclonal TBX3 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 6761 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesUMS; XHL; TBX3-ISO
WB Predicted band size79 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human TBX3
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody: P12632(TBX3 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P12632(TBX3 Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12632(TBX3 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于TBX3抗體的3篇參考文獻(xiàn)示例(內(nèi)容為虛構(gòu),僅供參考):

1. **文獻(xiàn)名稱**:*"Development and Validation of a TBX3-Specific Antibody for Immunohistochemical Analysis in Breast Cancer"*

**作者**:Smith A, et al.

**摘要**:本研究開(kāi)發(fā)了一種高特異性的TBX3抗體,用于檢測(cè)乳腺癌組織中TBX3蛋白的表達(dá)。通過(guò)免疫組化和Western blot驗(yàn)證,證實(shí)該抗體可有效區(qū)分TBX3與其他T-box家族蛋白,并發(fā)現(xiàn)TBX3高表達(dá)與患者預(yù)后不良相關(guān)。

2. **文獻(xiàn)名稱**:*"TBX3 in Limb Development: Antibody-Based Localization and Functional Studies"*

**作者**:Chen L, et al.

**摘要**:利用兔源多克隆TBX3抗體,揭示了TBX3在小鼠胚胎肢芽發(fā)育中的時(shí)空表達(dá)模式。研究發(fā)現(xiàn)TBX3缺失導(dǎo)致肢體形態(tài)異常,抗體染色進(jìn)一步證實(shí)其與FGF信號(hào)通路的相互作用。

3. **文獻(xiàn)名稱**:*"TBX3 Antibody Application in Cardiac Conduction System Mapping"*

**作者**:Rodriguez M, et al.

**摘要**:通過(guò)特異性TBX3抗體標(biāo)記,證實(shí)TBX3在心臟房室結(jié)中的特異性表達(dá),并發(fā)現(xiàn)其在心臟起搏細(xì)胞分化中的關(guān)鍵作用。研究為心律失常機(jī)制提供了新見(jiàn)解。

4. **文獻(xiàn)名稱**:*"A Comparative Study of Commercial TBX3 Antibodies for Flow Cytometry"*

**作者**:Tanaka K, et al.

**摘要**:評(píng)估了五種市售TBX3抗體的特異性與靈敏度,推薦克隆號(hào)H-9適用于流式細(xì)胞術(shù),并成功應(yīng)用于黑色素瘤細(xì)胞系的TBX3蛋白定量分析。

(注:以上文獻(xiàn)為示例,實(shí)際引用時(shí)需以真實(shí)出版物為準(zhǔn)。)

       

背景信息

The TBX3 antibody is a crucial tool in studying the TBX3 protein, a member of the T-box transcription factor family. TBX3 plays pivotal roles in embryonic development, particularly in limb, heart, and organogenesis. It shares functional overlap with TBX5. and both regulate gene networks involved in cell differentiation, proliferation, and tissue patterning. Notably, TBX3 is implicated in suppressing the Hippo signaling pathway, influencing organ size and tumorigenesis. Dysregulation of TBX3 expression is linked to developmental disorders like ulnar-mammary syndrome (caused by TBX3 mutations) and cancers, including breast cancer, melanoma, and hepatocellular carcinoma, where it often promotes metastasis and chemoresistance.

TBX3 antibodies are primarily used in research to detect and quantify TBX3 protein levels via techniques like Western blotting, immunohistochemistry, and immunofluorescence. These antibodies aid in elucidating TBX3's spatial-temporal expression, post-translational modifications, and interactions with signaling pathways. Commercial TBX3 antibodies are typically raised against specific epitopes (e.g., human TBX3 amino acid regions) and vary in clonality (monoclonal/polyclonal), host species, and validation standards. Challenges include ensuring specificity due to homology within the T-box family and cross-reactivity risks. Recent studies leverage TBX3 antibodies to explore its dual role as a tumor suppressor or oncogene, depending on context, and its potential as a therapeutic target. Validation using knockout controls or siRNA is critical for reliable experimental outcomes.

       
關(guān)鍵字: TBX3抗體;TBX3;TBX3 Antibody;

公司簡(jiǎn)介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,植物生物技術(shù),細(xì)胞培養(yǎng),蛋白組學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

TBX3抗體;TBX3 Antibody—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
詢價(jià)
VIP5年
上海冠導(dǎo)生物工程有限公司
2025-08-13
¥1098
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-12
¥3104
VIP4年
上海博爾森生物科技有限公司
2025-08-12
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