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SMOC2抗體,Rabbit Polyclonal SMOC2 Antibody
  • SMOC2抗體,Rabbit Polyclonal SMOC2 Antibody
  • SMOC2抗體,Rabbit Polyclonal SMOC2 Antibody
  • SMOC2抗體,Rabbit Polyclonal SMOC2 Antibody

SMOC2抗體;SMOC2 Antibody—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-26
QQ交談 微信洽談

產品詳情

中文名稱:SMOC2抗體英文名稱:Rabbit Polyclonal SMOC2 Antibody
品牌: 艾普蒂產地: 武漢
保存條件: Stored at -20°C for 6516 year. Avoid repeated freeze / thaw cycles.產品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: SMOC2
2025-05-26 SMOC2抗體 Rabbit Polyclonal SMOC2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 6516 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產品詳情

AliasesDTDP1; SMAP2; MST117; MSTP117; MSTP140; bA37D8.1; bA270C4A.1; dJ421D16.1
WB Predicted band size50 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human SMOC2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: P12220(SMOC2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P12220(SMOC2 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12220(SMOC2 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

參考文獻

以下是關于SMOC2抗體的3篇參考文獻示例(部分信息基于假設性內容整理,實際文獻需通過學術數據庫驗證):

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1. **文獻名稱**: *"A monoclonal antibody targeting SMOC2 inhibits tumor growth in pancreatic cancer models"*

**作者**: Li, Y., et al.

**摘要**: 本研究開發(fā)了一種針對SMOC2的小鼠單克隆抗體,驗證了其在胰腺癌組織中的特異性結合能力。實驗表明,該抗體可通過阻斷SMOC2與整合素相互作用抑制腫瘤細胞遷移和體內腫瘤生長。

2. **文獻名稱**: *"SMOC2 expression in cardiac fibrosis: Validation of a custom polyclonal antibody for immunohistochemistry"*

**作者**: Garcia-Ramirez, M., et al.

**摘要**: 作者制備并驗證了一種兔源多克隆抗體,用于檢測心臟纖維化模型中的SMOC2蛋白。抗體在免疫組化(IHC)和免疫印跡(WB)中表現(xiàn)出高特異性,證實SMOC2在纖維化區(qū)域顯著上調。

3. **文獻名稱**: *"Development of a sensitive ELISA for SMOC2 detection in serum using a novel antibody pair"*

**作者**: Watanabe, K., et al.

**摘要**: 研究團隊篩選出針對SMOC2不同表位的單克隆抗體,并建立了一種高靈敏度的ELISA檢測方法。該抗體對能夠檢測血清中低濃度的SMOC2.為癌癥早期診斷提供了潛在工具。

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**提示**:以上為示例性內容,實際文獻需通過PubMed、Web of Science等平臺檢索。建議使用關鍵詞“SMOC2 antibody”、“SMOC2 immunoassay”或結合具體應用場景(如“SMOC2 cancer”)查找近期研究。部分商業(yè)抗體的驗證數據也可參考供應商網站(如Abcam、Sigma-Aldrich的產品說明書引用文獻)。

       

背景信息

SMOC2 (Secreted Modular Calcium-Binding Protein 2) is a member of the SPARC (Secreted Protein Acidic and Rich in Cysteine) family, characterized by its modular structure containing follistatin-like and calcium-binding domains. It is expressed in various tissues and plays roles in extracellular matrix (ECM) organization, cell adhesion, and tissue development. SMOC2 is implicated in regulating cellular processes such as proliferation, differentiation, and angiogenesis through interactions with growth factors (e.g., BMPs) and integrin-mediated signaling pathways.

Antibodies targeting SMOC2 are essential tools for studying its expression, localization, and function in physiological and pathological contexts. They are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect SMOC2 in tissue samples or cell cultures. Research has linked SMOC2 overexpression to diseases such as cancer (e.g., promoting tumor progression and metastasis in colorectal, liver, and breast cancers) and fibrotic disorders (e.g., liver and lung fibrosis). Its role in embryonic development, particularly in organogenesis and tissue repair, also makes it a focus in regenerative medicine studies. SMOC2 antibodies aid in elucidating its dual roles in ECM homeostasis and disease mechanisms, offering potential as a biomarker or therapeutic target. Most commercial SMOC2 antibodies are raised against specific epitopes using recombinant proteins or synthetic peptides, validated for species reactivity (human, mouse, rat) and application-specific performance.

       
關鍵字: SMOC2抗體;SMOC2;SMOC2 Antibody;

公司簡介

生物技術有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數 1-10人 年營業(yè)額 ¥ 100萬以內
主營行業(yè) 抗體,植物生物技術,細胞培養(yǎng),蛋白組學 經營模式 貿易,工廠,試劑,定制,服務
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產品:生物試劑
  • 公司地址:青浦
詢盤

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