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GM130抗體,Rabbit Monoclonal GM130 Antibody
  • GM130抗體,Rabbit Monoclonal GM130 Antibody
  • GM130抗體,Rabbit Monoclonal GM130 Antibody
  • GM130抗體,Rabbit Monoclonal GM130 Antibody

GM130抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-23
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:GM130抗體英文名稱:Rabbit Monoclonal GM130 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 7804 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: GM130
2025-05-23 GM130抗體 Rabbit Monoclonal GM130 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 7804 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat,Cow,Dog
IF1/20-1/50 Human,Mouse,Rat,Cow,Dog
IHCIHC:1/100-1/200;IHF:1/50-1/200 Human,Mouse,Rat,Cow,Dog
ICC1/50-1/200 Human,Mouse,Rat,Cow,Dog
FCM咨詢技術(shù) Human,Mouse,Rat,Cow,Dog
Elisa咨詢技術(shù) Human,Mouse,Rat,Cow,Dog
   

產(chǎn)品詳情

AliasesGM130; Gm130 autoantigen; GOLGA 2; Golga2; Golgi autoantigen; Golgin 95;;Golgin subfamily A member 2
WB Predicted band sizeCalculated MW: 113 kDa ; Observed MW: 130 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat,Monkey,Cow,Dog
ImmunogenA synthesized peptide derived from human Golgin subfamily A member 2
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    


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       All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    


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       All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    


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       Immunofluorescent analysis using the Antibody at 1:200 dilution.    


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       Immunohistochemical analysis of paraffin-embedded human cervix carcinoma, using GM130 Antibody.    


           

參考文獻(xiàn)

以下是關(guān)于GM130抗體的3篇參考文獻(xiàn)的簡要概括:

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1. **文獻(xiàn)名稱**:*GM130. a cis-Golgi protein, is a member of the SNAP receptor complex*

**作者**:Nakamura N, et al.

**摘要**:該研究通過GM130抗體的免疫沉淀分析,揭示了GM130作為順面高爾基體基質(zhì)蛋白,參與維持高爾基體結(jié)構(gòu)的完整性,并與SNAP受體復(fù)合物相互作用,調(diào)控囊泡運輸過程。

2. **文獻(xiàn)名稱**:*The Golgi matrix protein GM130: a specific marker of interphase Golgi in mammalian cells*

**作者**:Barr FA, et al.

**摘要**:作者利用GM130抗體進(jìn)行免疫熒光和電鏡研究,證實GM130在細(xì)胞間期特異性標(biāo)記高爾基體,并在有絲分裂期間隨高爾基體解體而分散,為研究高爾基體動態(tài)提供了關(guān)鍵工具。

3. **文獻(xiàn)名稱**:*GRASP65 and GM130 synergistically regulate Golgi morphology and trafficking*

**作者**:Shorter J, et al.

**摘要**:通過GM130抗體的功能抑制實驗,研究發(fā)現(xiàn)GM130與GRASP65協(xié)同調(diào)控高爾基體疊層形成,并影響蛋白質(zhì)分泌途徑,強調(diào)了其在細(xì)胞膜系統(tǒng)組織中的核心作用。

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以上文獻(xiàn)均以GM130抗體為核心實驗工具,探討了其在細(xì)胞器結(jié)構(gòu)、運輸及分裂中的功能。如需具體年份或期刊信息,可進(jìn)一步補充檢索。

       

背景信息

GM130. also known as Golgin subfamily A member 2 (GOLGA2), is a 130 kDa Golgi matrix protein encoded by the *GOLGA2* gene in humans. It is predominantly localized to the cis-Golgi network and plays a critical role in maintaining Golgi structure, vesicle trafficking, and glycosylation processes. GM130 interacts with other Golgi matrix proteins, such as GRASP65. to form the Golgi ribbon and ensure proper organelle stacking. Additionally, it participates in cell cycle regulation by contributing to Golgi disassembly and reassembly during mitosis.

GM130 antibodies are widely used tools in cell biology research to study Golgi morphology, dynamics, and functional disruptions. These antibodies, often raised in rabbits or mice, specifically recognize GM130 epitopes in techniques like immunofluorescence, Western blotting, and immunohistochemistry. Researchers rely on GM130 as a cis-Golgi marker to assess Golgi integrity in experimental models, including cancer, neurodegenerative diseases, and infectious diseases where Golgi fragmentation or dysfunction occurs. For example, altered GM130 expression has been linked to impaired protein trafficking in Alzheimer’s disease and disrupted cell division in certain cancers. When using GM130 antibodies, co-staining with other Golgi markers (e.g., TGN46 or Giantin) is recommended to validate subcellular localization and experimental outcomes.

       
關(guān)鍵字: GM130抗體;GM130;GM130 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

GM130抗體—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
詢價
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
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