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HPCAL4抗體,Rabbit Polyclonal HPCAL4 Antibody
  • HPCAL4抗體,Rabbit Polyclonal HPCAL4 Antibody
  • HPCAL4抗體,Rabbit Polyclonal HPCAL4 Antibody
  • HPCAL4抗體,Rabbit Polyclonal HPCAL4 Antibody

HPCAL4抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-21
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:HPCAL4抗體英文名稱:Rabbit Polyclonal HPCAL4 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 5546 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: HPCAL4
2025-05-21 HPCAL4抗體 Rabbit Polyclonal HPCAL4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 5546 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesHLP4
WB Predicted band size22 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human HPCAL4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebella tissue, Mouse brain tissue lysates, Primary antibody: P10460(HPCAL4 Antibody) at dilution 1/1300, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10460(HPCAL4 Antibody) at dilution 1/75. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于HPCAL4抗體的模擬參考文獻(xiàn)示例(注:文獻(xiàn)為虛構(gòu),僅作格式參考):

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1. **"Characterization of HPCAL4 Antibody for Detection of Calcium-Binding Proteins in Neuronal Tissues"**

*Authors: Zhang L, et al.*

摘要:本研究開發(fā)了一種針對HPCAL4蛋白的多克隆抗體,并通過Western blot和免疫組化驗證其特異性。實驗表明,該抗體能特異性識別腦組織中的HPCAL4.并揭示其在海馬體神經(jīng)元中的高表達(dá),提示其可能與突觸可塑性相關(guān)。

2. **"HPCAL4 Expression in Glioblastoma: A Prognostic Marker Study Using Immunohistochemistry"**

*Authors: Patel R, et al.*

摘要:通過商業(yè)化HPCAL4抗體(克隆號:ABX-204)分析膠質(zhì)母細(xì)胞瘤患者的組織樣本。研究發(fā)現(xiàn),HPCAL4高表達(dá)與患者生存期縮短顯著相關(guān),提示其作為腫瘤惡性程度的潛在生物標(biāo)志物。

3. **"Subcellular Localization of HPCAL4 in Retinal Photoreceptors: An Antibody-Based Imaging Approach"**

*Authors: Müller S, et al.*

摘要:利用免疫熒光技術(shù)結(jié)合HPCAL4抗體,首次報道了該蛋白在視網(wǎng)膜感光細(xì)胞中的亞細(xì)胞定位。結(jié)果顯示HPCAL4主要富集于纖毛基部,可能參與光信號轉(zhuǎn)導(dǎo)中的鈣離子調(diào)控。

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**備注**:若需真實文獻(xiàn),建議通過PubMed或Google Scholar以“HPCAL4 antibody”為關(guān)鍵詞檢索,并篩選涉及抗體驗證、蛋白功能或疾病關(guān)聯(lián)的研究。

       

背景信息

The HPCAL4 antibody targets the Hippocalcin-like 4 protein (HPCAL4), a member of the neuronal calcium sensor (NCS) family, which plays roles in calcium-mediated signaling pathways. HPCAL4. also known as VSNL1-like protein, is encoded by the HPCAL4 gene located on human chromosome 1q25.3. It contains EF-hand calcium-binding domains and is predominantly expressed in neuronal tissues, though its expression has also been detected in non-neuronal cells. HPCAL4 is implicated in regulating cellular processes such as synaptic plasticity, apoptosis, and intracellular trafficking by modulating calcium-dependent interactions with target proteins.

Antibodies against HPCAL4 are utilized in research to investigate its expression patterns, subcellular localization, and functional roles in both physiological and pathological contexts. For example, studies have explored its potential involvement in neurodegenerative diseases, cancer progression (e.g., prostate cancer), and neurodevelopmental disorders. Western blotting, immunohistochemistry, and immunofluorescence are common applications. However, HPCAL4's precise mechanisms remain less characterized compared to other NCS proteins like hippocalcin or neurocalcin. Commercial antibodies are typically validated for specificity via knockout controls or siRNA knockdown to ensure accurate detection. Ongoing research aims to clarify its interaction networks and therapeutic relevance in calcium-related pathologies.

       
關(guān)鍵字: HPCAL4抗體;HPCAL4;HPCAL4 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

HPCAL4抗體—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
詢價
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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