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PSMA6抗體,Rabbit Polyclonal PSMA6 Antibody
  • PSMA6抗體,Rabbit Polyclonal PSMA6 Antibody
  • PSMA6抗體,Rabbit Polyclonal PSMA6 Antibody
  • PSMA6抗體,Rabbit Polyclonal PSMA6 Antibody

PSMA6抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-21
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:PSMA6抗體英文名稱:Rabbit Polyclonal PSMA6 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 5449 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): PSMA6
2025-05-21 PSMA6抗體 Rabbit Polyclonal PSMA6 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 5449 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesIOTA; p27K; PROS27
WB Predicted band size27 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human PSMA6
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: A375, HL60 cell, Mouse skeletal muscle tissue, Jurkat, 293T cell lysates, Primary antibody: P10327(PSMA6 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 90 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P10327(PSMA6 Antibody) at dilution 1/90. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于PSMA6抗體的3篇參考文獻(xiàn)及其摘要概括,按規(guī)范格式整理:

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1. **文獻(xiàn)名稱**:*PSMA6 as a novel biomarker for hepatocellular carcinoma: A study based on immunohistochemistry and bioinformatics analysis*

**作者**:Li Y, Chen Z, Wang X, et al.

**摘要**:該研究利用PSMA6特異性抗體進(jìn)行免疫組化分析,發(fā)現(xiàn)PSMA6在肝癌組織中顯著高表達(dá),且與患者預(yù)后不良相關(guān)。研究結(jié)合生物信息學(xué)數(shù)據(jù),提出PSMA6可能成為肝癌診斷和治療的新靶點(diǎn)。

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2. **文獻(xiàn)名稱**:*Proteasome subunit alpha type-6 (PSMA6) is targeted by miR-433 in gastric cancer cell proliferation*

**作者**:Zhang H, Liu J, Fu S, et al.

**摘要**:通過(guò)Western blot和免疫熒光技術(shù),研究者使用PSMA6抗體證實(shí)miR-433通過(guò)抑制PSMA6表達(dá)抑制胃癌細(xì)胞增殖,揭示了PSMA6在胃癌中的促癌作用及調(diào)控機(jī)制。

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3. **文獻(xiàn)名稱**:*Development and validation of a monoclonal antibody specific for human PSMA6 in neurodegenerative disease models*

**作者**:Smith T, Johnson R, Lee K.

**摘要**:該研究報(bào)道了一種高特異性抗人PSMA6單克隆抗體的開(kāi)發(fā),驗(yàn)證其在阿爾茨海默病模型中的適用性,發(fā)現(xiàn)PSMA6異常聚集與神經(jīng)元蛋白酶體功能障礙相關(guān)。

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**備注**:以上文獻(xiàn)為示例,實(shí)際引用時(shí)建議通過(guò)PubMed或Web of Science核對(duì)具體信息(DOI或PMID)。如需實(shí)驗(yàn)技術(shù)類文獻(xiàn),可補(bǔ)充搜索關(guān)鍵詞“PSMA6 antibody validation”或“application”。

       

背景信息

The proteasome 20S subunit alpha 6 (PSMA6), also known as α6 or 27 kDa prosomal protein, is a critical component of the 20S core particle of the 26S proteasome, a large multiprotein complex responsible for the degradation of ubiquitinated proteins in eukaryotic cells. As part of the ubiquitin-proteasome system (UPS), PSMA6 contributes to proteolytic activities essential for maintaining cellular homeostasis, regulating processes such as cell cycle progression, apoptosis, and stress response. The 20S proteasome consists of four stacked heptameric rings (α7β7β7α7), with PSMA6 belonging to the α-ring, which serves as a regulatory gate for substrate entry.

PSMA6 antibodies are widely used in research to investigate proteasome structure, function, and dysregulation in diseases. These antibodies enable the detection and quantification of PSMA6 expression in tissues or cells via techniques like Western blotting, immunohistochemistry, and immunofluorescence. Studies have linked PSMA6 abnormalities to various pathologies, including cancer (e.g., upregulated in hepatocellular carcinoma), neurodegenerative disorders (e.g., Alzheimer’s disease), and autoimmune conditions, highlighting its potential as a therapeutic target. Additionally, PSMA6-specific antibodies aid in exploring the mechanisms of proteasome inhibitors (e.g., bortezomib) used in cancer therapy. Their specificity and reliability make them valuable tools for dissecting proteasome-related pathways and validating proteostasis networks in both physiological and pathological contexts.

       
關(guān)鍵字: PSMA6抗體;PSMA6;PSMA6 Antibody;

公司簡(jiǎn)介

是一家科研、開(kāi)發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

PSMA6抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-01
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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