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IMPA1抗體,Rabbit Polyclonal IMPA1 Antibody
  • IMPA1抗體,Rabbit Polyclonal IMPA1 Antibody
  • IMPA1抗體,Rabbit Polyclonal IMPA1 Antibody
  • IMPA1抗體,Rabbit Polyclonal IMPA1 Antibody

IMPA1抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-20
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:IMPA1抗體英文名稱:Rabbit Polyclonal IMPA1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4969 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): IMPA1
2025-05-20 IMPA1抗體 Rabbit Polyclonal IMPA1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4969 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesIMP; IMPA
WB Predicted band size30 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human IMPA1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human cerebrum tissue lysate, Primary antibody: P09639(IMPA1 Antibody) at dilution 1/360, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09639(IMPA1 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09639(IMPA1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是3-4條關(guān)于 **IMPA1抗體** 的模擬參考文獻(xiàn)(內(nèi)容為示例,非真實(shí)文獻(xiàn)):

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1. **文獻(xiàn)名稱**: *"Characterization of IMPA1-Specific Antibodies for Western Blot and Immunohistochemistry Applications"*

**作者**: Smith, J. et al.

**摘要**: 本研究驗(yàn)證了兩種IMPA1抗體的特異性,通過Western blot在人類和小鼠腦組織裂解液中檢測到約30 kDa的特異性條帶。免疫組化實(shí)驗(yàn)進(jìn)一步證實(shí)IMPA1在神經(jīng)元胞質(zhì)中的高表達(dá),支持其在肌醇代謝通路中的關(guān)鍵作用。

2. **文獻(xiàn)名稱**: *"IMPA1 Expression in Bipolar Disorder: A Comparative Study Using Antibody-Based Proteomic Analysis"*

**作者**: Cui, Y. & Zhang, L.

**摘要**: 通過ELISA和免疫熒光技術(shù),研究者比較了雙相情感障礙患者與健康對照者前額葉皮層中IMPA1蛋白水平的差異。結(jié)果顯示患者組IMPA1表達(dá)顯著降低,提示其與鋰鹽治療反應(yīng)相關(guān)的分子機(jī)制。

3. **文獻(xiàn)名稱**: *"Development of a Novel Monoclonal Antibody Against IMPA1 for Functional Studies in Neurodevelopmental Models"*

**作者**: Ohnishi, T. et al.

**摘要**: 文章報(bào)道了一種新型小鼠單克隆IMPA1抗體的開發(fā),并通過CRISPR敲除細(xì)胞系驗(yàn)證其特異性。該抗體成功用于流式細(xì)胞術(shù),揭示了IMPA1缺失對神經(jīng)元分化的影響。

4. **文獻(xiàn)名稱**: *"IMPA1 Antibody Localization in Mouse Brain: Implications for Inositol Biosynthesis Pathways"*

**作者**: Patel, R. & Williams, K.

**摘要**: 利用免疫組織化學(xué)和共聚焦顯微鏡,研究者繪制了IMPA1在小鼠海馬體和皮層中的亞細(xì)胞分布圖譜,發(fā)現(xiàn)其與內(nèi)質(zhì)網(wǎng)標(biāo)記物共定位,為肌醇磷酸酶活性的空間調(diào)控提供了新見解。

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如需真實(shí)文獻(xiàn),建議通過 **PubMed** 或 **Google Scholar** 檢索關(guān)鍵詞(如“IMPA1 antibody validation”或“IMPA1 protein expression”),并篩選近5年高被引研究。

       

背景信息

The IMPA1 (Inositol Monophosphatase 1) antibody is a tool used to detect the IMPA1 protein, a key enzyme in the inositol biosynthesis pathway. IMPA1 catalyzes the hydrolysis of inositol monophosphate to free inositol, a critical step in maintaining cellular inositol levels. This enzyme plays a vital role in the phosphatidylinositol (PI) signaling pathway, which regulates processes like neurotransmission, cell growth, and hormone response. IMPA1 is also a target of lithium, a mood stabilizer used in treating bipolar disorder, as lithium inhibits IMPA1 activity, modulating inositol recycling and downstream signaling.

Research on IMPA1 antibodies focuses on understanding its expression, localization, and function in health and disease. These antibodies are widely applied in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study IMPA1 distribution in tissues, particularly the brain, where it is highly expressed. Dysregulation of IMPA1 has been implicated in neuropsychiatric disorders (e.g., bipolar disorder, schizophrenia) and neurodegenerative conditions. Additionally, IMPA1 variants are linked to developmental delays and intellectual disabilities, emphasizing its role in neural function.

Antibodies specific to IMPA1 are validated for species reactivity (e.g., human, mouse, rat) and tested for cross-reactivity to ensure accuracy. They aid in exploring molecular mechanisms of lithium’s therapeutic effects and identifying biomarkers for related diseases. Commercial IMPA1 antibodies are often generated using recombinant proteins or peptide immunogens, with validation via knockout controls or siRNA knockdown. Their utility spans basic research, drug development, and clinical diagnostics.

       
關(guān)鍵字: IMPA1抗體;IMPA1;IMPA1 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

IMPA1抗體—艾普蒂相關(guān)廠家報(bào)價

產(chǎn)品名稱 價格   公司名稱 報(bào)價日期
¥1600.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-01
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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