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DDX39A抗體,Rabbit Polyclonal DDX39A Antibody
  • DDX39A抗體,Rabbit Polyclonal DDX39A Antibody
  • DDX39A抗體,Rabbit Polyclonal DDX39A Antibody
  • DDX39A抗體,Rabbit Polyclonal DDX39A Antibody

DDX39A抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-20
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:DDX39A抗體英文名稱:Rabbit Polyclonal DDX39A Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4948 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: DDX39A
2025-05-20 DDX39A抗體 Rabbit Polyclonal DDX39A Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4948 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesBAT1; DDXL; BAT1L; DDX39; URH49
WB Predicted band size49 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human DDX39A
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 231 and Jurkat cell lysates, Primary antibody: P09605(DDX39A Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09605(DDX39A Antibody) at dilution 1/65. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P09605(DDX39A Antibody) at dilution 1/65. (Original magnification: ×200)    


           

參考文獻

以下是3-4條關于 **DDX39A抗體** 的參考文獻示例(注:以下為模擬虛構內容,實際文獻請通過學術數(shù)據(jù)庫查詢):

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1. **文獻名稱**: *DDX39A interacts with the splicing machinery and promotes RNA splicing in human cells*

**作者**: Smith A, et al.

**摘要**: 本研究利用DDX39A特異性抗體進行免疫共沉淀(Co-IP)和免疫熒光實驗,發(fā)現(xiàn)DDX39A與剪接體復合物相互作用,并通過調控前體mRNA剪接影響基因表達。

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2. **文獻名稱**: *DDX39A expression correlates with cancer progression and immune infiltration*

**作者**: Zhang Y, et al.

**摘要**: 通過免疫組化(IHC)結合DDX39A抗體分析腫瘤組織樣本,發(fā)現(xiàn)DDX39A在多種癌癥中高表達,其水平與患者預后不良及腫瘤微環(huán)境中的免疫細胞浸潤相關。

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3. **文獻名稱**: *DDX39A is essential for viral RNA unwinding and innate immune signaling*

**作者**: Lee H, et al.

**摘要**: 使用DDX39A敲除細胞系及特異性抗體驗證,發(fā)現(xiàn)DDX39A通過解旋病毒RNA促進RIG-I信號通路激活,在抗病毒天然免疫應答中發(fā)揮關鍵作用。

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4. **文獻名稱**: *Structural insights into the ATP-dependent RNA helicase activity of DDX39A*

**作者**: Tanaka K, et al.

**摘要**: 通過抗體制備和冷凍電鏡技術解析DDX39A蛋白結構,揭示了其依賴ATP的RNA解旋酶活性機制,為靶向DDX39A的藥物設計提供依據(jù)。

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如需真實文獻,建議在 **PubMed** 或 **Google Scholar** 中檢索關鍵詞 "DDX39A antibody" 或結合具體研究場景篩選。

       

背景信息

DDX39A (also known as UAP56 or BAT1) is a member of the DEAD-box RNA helicase family, which plays critical roles in RNA metabolism, including pre-mRNA splicing, nuclear export, and translation. This ATP-dependent enzyme facilitates the unwinding of RNA secondary structures and participates in spliceosome assembly by recruiting key components to nascent transcripts. Dysregulation of DDX39A has been implicated in cancer, neurodegenerative diseases, and viral infections, highlighting its importance in cellular homeostasis.

Antibodies targeting DDX39A are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques such as Western blotting, immunofluorescence, and immunoprecipitation to investigate DDX39A's role in RNA processing and disease mechanisms. For instance, researchers employ these antibodies to analyze DDX39A overexpression in malignancies or its reduced activity in aging-related neurological disorders. Validated antibodies often undergo specificity checks using knockout cell lines or siRNA knockdown to ensure minimal cross-reactivity with homologous proteins like DDX39B. Commercial antibodies typically cite applications in detecting the ~50 kDa protein across human, mouse, and rat samples. Ongoing research also explores DDX39A's potential as a therapeutic target or biomarker, driving demand for reliable antibody reagents. Suppliers such as Abcam, Cell Signaling Technology, and Santa Cruz Biotechnology provide DDX39A antibodies, though performance may vary depending on epitope regions and experimental conditions.

       
關鍵字: DDX39A抗體;DDX39A;DDX39A Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內
主營行業(yè) 抗體,蛋白組學,細胞生物學 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

DDX39A抗體—艾普蒂相關廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥1600.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
¥1950
VIP3年
上海滬震實業(yè)有限公司
2025-08-01
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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