DCP2抗體—艾普蒂

價(jià)格	詢價(jià)
包裝	20μl	50μl	100μl

最小起訂量	1μl
發(fā)貨地	上海
更新日期	2025-05-20

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產(chǎn)品詳情

中文名稱:DCP2抗體	英文名稱:Rabbit Polyclonal DCP2 Antibody
品牌: 艾普蒂	產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4940 year. Avoid repeated freeze / thaw cycles.	產(chǎn)品類別: 抗體
重組: 否	應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat	宿主: Rabbit
偶聯(lián)物: 無(wú)	靶點(diǎn): DCP2

驗(yàn)證與應(yīng)用

應(yīng)用及物種

WB	咨詢技術(shù)	Human,Mouse,Rat
IF	咨詢技術(shù)	Human,Mouse,Rat
IHC	1/30-1/150	Human,Mouse,Rat
ICC	技術(shù)咨詢	Human,Mouse,Rat
FCM	咨詢技術(shù)	Human,Mouse,Rat
Elisa	1/5000-1/10000	Human,Mouse,Rat

產(chǎn)品詳情

Aliases	NUDT20
WB Predicted band size	48 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human DCP2
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HL-60 cell lysate, Primary antibody: P09593(DCP2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09593(DCP2 Antibody) at dilution 1/45. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P09593(DCP2 Antibody) at dilution 1/45. (Original magnification: ×200)

參考文獻(xiàn)

以下是關(guān)于DCP2抗體的3篇參考文獻(xiàn)的簡(jiǎn)要概括(文獻(xiàn)為虛構(gòu)示例，僅作參考)：

1. **文獻(xiàn)名稱**: "DCP2 as a Novel Diagnostic Biomarker in Hepatocellular Carcinoma: Immunohistochemical Analysis"

**作者**: Li, X. et al.

**摘要**: 本研究通過(guò)免疫組化(IHC)和Western blot技術(shù)，使用特異性DCP2抗體檢測(cè)肝細(xì)胞癌(HCC)組織中DCP2蛋白的表達(dá)水平，發(fā)現(xiàn)其過(guò)表達(dá)與腫瘤進(jìn)展和不良預(yù)后顯著相關(guān)，提示DCP2可能作為HCC的潛在診斷標(biāo)志物。

2. **文獻(xiàn)名稱**: "The Role of DCP2 in mRNA Decapping and Antiviral Immune Response"

**作者**: Wang, Y. et al.

**摘要**: 文章利用DCP2抗體進(jìn)行免疫共沉淀(Co-IP)和免疫熒光實(shí)驗(yàn)，驗(yàn)證了DCP2在細(xì)胞質(zhì)mRNA脫帽復(fù)合體中的核心作用，并發(fā)現(xiàn)其與病毒RNA降解過(guò)程的關(guān)聯(lián)，為抗病毒治療提供新靶點(diǎn)。

3. **文獻(xiàn)名稱**: "DCP2 Knockdown Inhibits Colorectal Cancer Metastasis via Regulating mRNA Stability"

**作者**: Smith, J. et al.

**摘要**: 研究通過(guò)siRNA敲低DCP2并結(jié)合DCP2抗體的Western blot驗(yàn)證，證明DCP2通過(guò)調(diào)控促癌mRNA的穩(wěn)定性影響結(jié)直腸癌轉(zhuǎn)移，為靶向DCP2的癌癥治療提供依據(jù)。

4. **文獻(xiàn)名稱**: "DCP2 Antibody-Based Detection of Neuronal mRNA Decapping in Neurodegeneration"

**作者**: Nakamura, K. et al.

**摘要**: 通過(guò)DCP2抗體進(jìn)行腦組織切片染色，揭示了DCP2在阿爾茨海默病模型中的異常分布，表明其可能通過(guò)調(diào)節(jié)神經(jīng)元mRNA代謝參與神經(jīng)退行性病變機(jī)制。

(注：以上文獻(xiàn)為模擬內(nèi)容，實(shí)際引用需查詢真實(shí)數(shù)據(jù)庫(kù)如PubMed或Web of Science。)

背景信息

The DCP2 (Decapping Enzyme 2) antibody is a tool used to study the DCP2 protein, a critical component of the mRNA decapping complex in eukaryotic cells. DCP2 functions as a catalytic subunit within this complex, partnering with DCP1 and other regulatory proteins to remove the protective 5' cap structure from mRNAs, marking them for degradation by exonucleases. This process is essential for regulating mRNA turnover, controlling gene expression, and maintaining cellular homeostasis. DCP2-mediated decapping is tightly regulated and plays a role in diverse biological processes, including stress responses, development, and cell cycle progression.

Antibodies targeting DCP2 enable researchers to investigate its expression levels, subcellular localization, and interactions with other proteins. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to explore how DCP2 contributes to mRNA decay pathways or dysregulation in diseases. For example, altered DCP2 activity has been linked to neurological disorders, cancers, and viral infections, where disrupted mRNA stability may drive pathological processes. By studying DCP2. scientists aim to uncover mechanisms underlying post-transcriptional gene regulation and identify potential therapeutic targets. The DCP2 antibody thus serves as a key reagent in molecular and cellular biology research focused on RNA metabolism and its broader physiological implications.

關(guān)鍵字： DCP2抗體;DCP2;DCP2 Antibody;

公司簡(jiǎn)介

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成立日期	2024-07-02 （2年）	注冊(cè)資本	20萬(wàn)人民幣
員工人數(shù)	1-10人	年?duì)I業(yè)額	￥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè)	抗體,蛋白組學(xué),細(xì)胞生物學(xué)	經(jīng)營(yíng)模式	貿(mào)易,工廠,試劑,定制,服務(wù)

上海切爾齊生物科技有限公司

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公司成立：2年
注冊(cè)資本：20萬(wàn)人民幣
企業(yè)類型：有限責(zé)任公司(自然人投資或控股)
主營(yíng)產(chǎn)品：重組蛋白、抗體、生物試劑
公司地址：青浦區(qū)

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