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CYP4F12抗體,Rabbit Polyclonal CYP4F12 Antibody
  • CYP4F12抗體,Rabbit Polyclonal CYP4F12 Antibody
  • CYP4F12抗體,Rabbit Polyclonal CYP4F12 Antibody
  • CYP4F12抗體,Rabbit Polyclonal CYP4F12 Antibody

CYP4F12抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-20
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CYP4F12抗體英文名稱:Rabbit Polyclonal CYP4F12 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4926 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: CYP4F12
2025-05-20 CYP4F12抗體 Rabbit Polyclonal CYP4F12 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4926 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesCYPIVF12; F22329_1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CYP4F12
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P09577(CYP4F12 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09577(CYP4F12 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于CYP4F12抗體的模擬參考文獻(xiàn)示例(實際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫驗證):

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1. **文獻(xiàn)名稱**: *"Development and Application of a CYP4F12-Specific Monoclonal Antibody for Immunohistochemical Analysis"*

**作者**: Zhang L, et al.

**摘要**: 本研究開發(fā)了一種高特異性CYP4F12單克隆抗體,驗證其在人肝臟和腸道組織中的表達(dá)定位,證實其在藥物代謝和脂質(zhì)氧化研究中的實用性。

2. **文獻(xiàn)名稱**: *"CYP4F12 Expression in Atopic Dermatitis: Correlation with Skin Barrier Dysfunction"*

**作者**: Müller R, et al.

**摘要**: 通過Western blot和免疫組化技術(shù),利用CYP4F12抗體發(fā)現(xiàn)其在特應(yīng)性皮炎患者表皮中表達(dá)下調(diào),提示其與皮膚屏障功能受損相關(guān)。

3. **文獻(xiàn)名稱**: *"CYP4F12-Mediated Eicosanoid Metabolism in Colorectal Cancer Progression"*

**作者**: Tanaka K, et al.

**摘要**: 研究使用CYP4F12抗體檢測結(jié)直腸癌組織,發(fā)現(xiàn)其表達(dá)水平與前列腺素代謝通路激活及患者預(yù)后不良顯著相關(guān)。

4. **文獻(xiàn)名稱**: *"Functional Characterization of CYP4F12 in Drug Metabolism Using siRNA and Antibody-Based Inhibition"*

**作者**: Johnson B, et al.

**摘要**: 結(jié)合CYP4F12抗體與基因沉默技術(shù),揭示該酶在肝細(xì)胞中對特定藥物的氧化代謝作用,為個體化用藥提供依據(jù)。

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**建議**:以上為模擬示例,實際文獻(xiàn)請通過PubMed、Google Scholar等平臺以“CYP4F12 antibody”或“CYP4F12 immunohistochemistry”為關(guān)鍵詞檢索。

       

背景信息

The CYP4F12 antibody is a tool used to detect and study the cytochrome P450 family 4 subfamily F member 12 (CYP4F12) enzyme, which plays a role in metabolizing endogenous and exogenous compounds. CYP4F12 is part of the cytochrome P450 superfamily, known for oxidizing fatty acids, eicosanoids, and xenobiotics. This enzyme is primarily expressed in the liver, kidneys, and intestines, contributing to the metabolism of arachidonic acid derivatives, including leukotriene B4 and hydroxyeicosatetraenoic acids (HETEs), as well as certain drugs. Its genetic locus is on chromosome 19p13.12.

Research using CYP4F12 antibodies focuses on understanding its physiological roles, such as regulating inflammatory responses, lipid homeostasis, and drug clearance. These antibodies are essential in techniques like Western blotting, immunohistochemistry, and immunofluorescence to analyze protein expression, tissue distribution, and subcellular localization (e.g., endoplasmic reticulum or mitochondria). Dysregulation of CYP4F12 has been implicated in diseases like hypertension, cancer, and metabolic disorders, making its study clinically relevant. Monoclonal or polyclonal CYP4F12 antibodies are validated for specificity to ensure accurate detection, aiding investigations into enzyme function, genetic variants, and therapeutic targeting. Ongoing studies explore its interactions with lipid signaling pathways and potential as a biomarker or drug target.

       
關(guān)鍵字: CYP4F12抗體;CYP4F12;CYP4F12 Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

CYP4F12抗體—艾普蒂相關(guān)廠家報價

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2025-07-14
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