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CNBP抗體,Rabbit Polyclonal CNBP Antibody
  • CNBP抗體,Rabbit Polyclonal CNBP Antibody
  • CNBP抗體,Rabbit Polyclonal CNBP Antibody
  • CNBP抗體,Rabbit Polyclonal CNBP Antibody

CNBP抗體—艾普蒂

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-20
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CNBP抗體英文名稱:Rabbit Polyclonal CNBP Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4892 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): CNBP
2025-05-20 CNBP抗體 Rabbit Polyclonal CNBP Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4892 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesDM2; ZNF9; CNBP1; PROMM; RNF163; ZCCHC22
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CNBP
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09527(CNBP Antibody) at dilution 1/65. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P09527(CNBP Antibody) at dilution 1/65. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是3-4條關(guān)于 **CNBP抗體** 的模擬參考文獻(xiàn)(內(nèi)容為虛構(gòu)示例,供參考):

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1. **文獻(xiàn)名稱**:*"CNBP Aggregation in Neurodegenerative Diseases: Antibody-Based Detection in ALS/FTD Models"*

**作者**:Smith J. et al. (2021)

**摘要**:研究利用特異性CNBP抗體在肌萎縮側(cè)側(cè)索硬化癥(ALS)和額顳葉癡呆(FTD)患者腦組織中發(fā)現(xiàn)CNBP蛋白異常聚集,提示其在神經(jīng)退行性疾病中可能通過(guò)RNA代謝失調(diào)驅(qū)動(dòng)病理進(jìn)程。

2. **文獻(xiàn)名稱**:*"Cellular Localization of CNBP in Stress Granules: A Role in Phase Separation"*

**作者**:Johnson R. et al. (2020)

**摘要**:通過(guò)免疫熒光和共聚焦顯微鏡技術(shù),使用CNBP抗體揭示了該蛋白在細(xì)胞應(yīng)激條件下參與應(yīng)激顆粒(stress granules)的形成,并調(diào)控RNA-蛋白相分離過(guò)程的分子機(jī)制。

3. **文獻(xiàn)名稱**:*"CNBP Expression Profiling in Glioblastoma via Immunohistochemistry"*

**作者**:Lee H. et al. (2019)

**摘要**:采用CNBP特異性抗體對(duì)膠質(zhì)母細(xì)胞瘤組織進(jìn)行免疫組化分析,發(fā)現(xiàn)CNBP在腫瘤細(xì)胞中高表達(dá),并與患者預(yù)后不良相關(guān),可能作為潛在治療靶點(diǎn)。

4. **文獻(xiàn)名稱**:*"Functional Characterization of CNBP Antibodies in Myotonic Dystrophy Models"*

**作者**:Brown K. et al. (2018)

**摘要**:研究通過(guò)Western blot和免疫沉淀驗(yàn)證了CNBP抗體在肌強(qiáng)直性營(yíng)養(yǎng)不良模型中的特異性,證實(shí)CNBP與CAG重復(fù)RNA的異常結(jié)合導(dǎo)致肌肉細(xì)胞功能缺陷。

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(注:以上文獻(xiàn)為示例性內(nèi)容,實(shí)際研究中請(qǐng)通過(guò)PubMed或Google Scholar檢索真實(shí)文獻(xiàn)。)

       

背景信息

The CNBP antibody targets the Cellular Nucleic Acid Binding Protein (CNBP), also known as zinc finger protein 9 (ZNF9), a highly conserved protein encoded by the CNBP gene. CNBP is a single-stranded nucleic acid-binding protein containing seven zinc knuckles, which facilitate interactions with DNA and RNA. It plays a regulatory role in transcription and translation, influencing processes such as ribosomal RNA synthesis, mRNA stability, and translational control. CNBP is implicated in cellular proliferation, differentiation, and apoptosis, with roles in embryonic development and tissue homeostasis.

Research highlights its association with neuromuscular disorders, particularly myotonic dystrophy type 2 (DM2), where abnormal CCTG repeat expansions in the CNBP gene disrupt RNA processing. Antibodies against CNBP are essential tools for studying its expression, localization, and function in both physiological and pathological contexts. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to investigate CNBP's involvement in diseases, including neurodegeneration, cancer, and muscle atrophy. Recent studies also explore its potential role in RNA granule dynamics and stress response pathways. Despite progress, the precise molecular mechanisms of CNBP remain under investigation, underscoring the importance of specific antibodies for ongoing research.

       
關(guān)鍵字: CNBP抗體;CNBP;CNBP Antibody;

公司簡(jiǎn)介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

CNBP抗體—艾普蒂相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
¥1950
VIP3年
上海滬震實(shí)業(yè)有限公司
2025-08-01
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費(fèi)雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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