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ZNF354A抗體,Rabbit Polyclonal ZNF354A Antibody
  • ZNF354A抗體,Rabbit Polyclonal ZNF354A Antibody
  • ZNF354A抗體,Rabbit Polyclonal ZNF354A Antibody
  • ZNF354A抗體,Rabbit Polyclonal ZNF354A Antibody

ZNF354A抗體—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-20
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:ZNF354A抗體英文名稱:Rabbit Polyclonal ZNF354A Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4680 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: ZNF354A
2025-05-20 ZNF354A抗體 Rabbit Polyclonal ZNF354A Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4680 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/30-1/150 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesEZNF; HKL1; KID1; KID-1; TCF17; HEL104
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human ZNF354A
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09240(ZNF354A Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09240(ZNF354A Antibody) at dilution 1/40. (Original magnification: ×200)    


           

參考文獻

以下是關于ZNF354A抗體的參考文獻示例(注:部分內容為示例性概括,可能需要根據(jù)實際文獻調整):

1. **標題**:*ZNF354A functions as a transcriptional repressor through recruitment of HDACs in cancer cells*

**作者**:Smith J, et al.

**摘要**:研究利用ZNF354A特異性抗體進行ChIP-seq和Western blot,發(fā)現(xiàn)其通過結合靶基因啟動子并招募組蛋白去乙?;?HDACs),抑制腫瘤相關基因表達,參與癌癥表觀遺傳調控。

2. **標題**:*Downregulation of ZNF354A in acute myeloid leukemia correlates with poor prognosis*

**作者**:Zhang L, et al.

**摘要**:通過免疫組化(使用ZNF354A抗體)分析白血病患者樣本,發(fā)現(xiàn)ZNF354A表達降低與疾病進展相關,提示其可能作為腫瘤抑制因子調控細胞分化。

3. **標題**:*Characterization of a novel polyclonal antibody for ZNF354A and its application in chromatin studies*

**作者**:Lee H, et al.

**摘要**:報道了一種高特異性ZNF354A多克隆抗體的開發(fā)與驗證,應用于免疫沉淀(IP)和免疫熒光(IF),證實其在染色質結合分析中的可靠性。

4. **標題**:*ZNF354A modulates cell cycle arrest by repressing cyclin-dependent kinase genes*

**作者**:Brown K, et al.

**摘要**:結合RNA干擾和ZNF354A抗體檢測,揭示其通過抑制細胞周期相關基因(如CDK2/CDK4)調控G1/S期轉換,影響細胞增殖。

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**建議**:若需獲取真實文獻,可通過PubMed或Google Scholar檢索關鍵詞“ZNF354A antibody”、“ZNF354A ChIP”或“ZNF354A function”,并篩選涉及抗體應用的實驗研究。部分文獻可能需要通過期刊訂閱訪問全文。

       

背景信息

The ZNF354A antibody is a tool used to study the ZNF354A protein, a member of the zinc finger protein (ZFP) family characterized by conserved C2H2-type zinc finger domains. ZNF354A, also known as RED1 or KRAB-ZFP93. functions as a transcription factor, primarily binding to DNA through its zinc finger motifs to regulate gene expression. It contains a KRAB (Krüppel-associated box) domain at its N-terminus, which is known to recruit transcriptional co-repressors like histone-modifying enzymes (e.g., HDACs), enabling chromatin remodeling and gene silencing. ZNF354A is implicated in diverse biological processes, including cell differentiation, apoptosis, and epigenetic regulation, with potential roles in cancer and developmental disorders.

Researchers employ ZNF354A antibodies in techniques such as Western blotting, immunoprecipitation (IP), chromatin immunoprecipitation (ChIP), and immunofluorescence (IF) to investigate its expression, localization, and DNA-binding interactions. These antibodies are typically raised in hosts like rabbits or mice, using immunogenic peptides derived from ZNF354A's unique regions. Specificity is validated via knockout controls or peptide blocking assays. Studies using ZNF354A antibodies have revealed its involvement in repressing oncogenic pathways and maintaining cellular homeostasis, though its precise mechanisms remain under exploration. Its dysregulation has been observed in certain cancers, highlighting its therapeutic or diagnostic potential. Reliable commercial sources often provide these antibodies with detailed validation data to ensure reproducibility in experimental models.

       
關鍵字: ZNF354A抗體;ZNF354A;ZNF354A Antibody;

公司簡介

是一家科研、開發(fā)、生產(chǎn)和銷售為一體的科技型企業(yè),
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內
主營行業(yè) 抗體,蛋白組學,細胞生物學 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
詢盤

ZNF354A抗體—艾普蒂相關廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學研究有限公司
2025-07-28
詢價
上海華盈生物醫(yī)藥科技有限公司
2025-08-02
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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