描述（Description）
IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15 is essential for the development and function natural killer (NK) cell, NKT cell and memory (m) CD8+ T cell[1]. IL-15R alpha maintains memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha/IL-15 complex can activate the antitumor functions of NK cells and CD8+ T cells[2][3]. IL-15R alpha & IL-15 Protein, Human (HEK293, Fc) is a recombinant human IL-15R alpha (I31-D96) & IL-15 (N49-S162) fusion protein with a C-Terminal hFc tag, which is produced in HEK293 cells.
純度（Purity）
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining)
生物活性（Bioactivity）
Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The EC50 for this effect is＜60ng/ml.
氨基酸序列（Target Protein Sequence）
ITCPPPMSVEHADIWVKSYSLYSRERYICNSGFKRKAGTSSLTECVLNKATNVAHWTTPSLKCIRD&NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANDSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
制劑（Trait）
Lyophilized from a 0.22 μm-filtered solution containing 0.085% TFA,30%ACN, 5% mannitol, pH 2.5
復溶（Reconstitution）
It is recommended to redissolve in sterile deionized water.
保存條件&效期（Storage & Stability）
Stored at -20°C for 1 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.Please avoid repeated freeze-thaw cycles.
運輸方式(Shipping)
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
生物活性（Bioactivity）
Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml,corresponding to a specific bioactivity of ≥ 5 x 105 units/mg.
電泳（SDS-PAGE）
Greater than 95% as determined by reducing SDS-PAGE.
特別提示：本公司的所有產(chǎn)品僅用于工業(yè)應用或者科學研究等非醫(yī)療目的,不可用于人類或動物的臨床診斷或者治療,非藥用,非食用。
關鍵字： GMP級;高純度;批間一致;生物活性;科研專供;
在生物科技領域，豐度蛋白專注重組蛋白供應，以“豐度的風帆為蛋白提供動力，豐度為蛋白護航”為使命，賦能生命科學發(fā)展。
蘇州豐度依托先進技術平臺，打造成熟生產(chǎn)體系，嚴控基因工程設計、細胞培養(yǎng)、蛋白純化等環(huán)節(jié)，優(yōu)化工藝與管理，確保產(chǎn)品高純度、高活性且批間一致。產(chǎn)品覆蓋基礎研究、生物醫(yī)藥研發(fā)等多領域，為科研及生產(chǎn)提供多樣、適配產(chǎn)品，助力突破技術難題 。